Microfluidic valves comprising nanolayered thermoresponsive polymer-grafted capillaries

被引:58
作者
Idota, N
Kikuchi, A
Kobayashi, J
Sakai, K
Okano, T
机构
[1] Tokyo Womens Med Univ, Inst Adv Biomed Engn Sci & Sci, Ctr Excellence COE Program 21st Century, Tokyo 1628666, Japan
[2] Waseda Univ, Ctr Excellence COE Program 21st Century, Dept Appl Chem, Tokyo 1698555, Japan
关键词
D O I
10.1002/adma.200402068
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Thermally regulated flow control using a thermoresponsive polymer grafted onto surfaces of capillary lumen facilitates rapid, reliable, and repeatable open-close cycles (see Figure). Hydration of the grafted polymer chains on the internal surfaces may increase the microviscosity of the hydration layers at the wall interfaces without physically occluding the lumen, producing complete and reversible on/off flow valving in microchannels under hydrostatic pressures relevant for microfluidics approaches.
引用
收藏
页码:2723 / +
页数:6
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