Synthesis of magnetoliposomes with monodisperse iron oxide nanocrystal cores for hyperthermia

被引：139

作者：

Gonzales, M ^{[1
]}

Krishnan, KM ^{[1
]}

机构：

[1] Univ Washington, Dept Mat Sci & Engn, Seattle, WA 98195 USA

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期

关键词：

magnetic hyperthermia; lipid bilayer; magnetite; nanoparticles; superparamagnetic Fe(CO)(5); magnetoliposomes;

D O I：

10.1016/j.jmmm.2005.02.020

中图分类号：

T [工业技术];

学科分类号：

08 [工学];

摘要：

Heating rates generated by superparamagnetic particles deteriorate quickly with particle polydispersity. We prepared highly uniform, monodisperse, single-crystal magnetite nanoparticles of tailorable size via organometallic decomposition. As-synthesized nanocrystals were coated with phospholipids to form biocompatible magnetoliposomes. Modeling of AC-magnetic field parameters indicates that 11 nm nanocrystals have maximum heating rates within the biologically safe frequency range. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：265 / 270

页数：6

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