A labdane diterpene glucoside from the rhizomes of Curcuma mangga

被引：72

作者：

Abas, F

Lajis, NH ^{[1
]}

Shaari, H

Israf, DA

Stanslas, J

Yusuf, UK

Raof, SM

机构：

[1] Univ Putra Malaysia, Fac Med & Hlth Sci, Inst Biosci, Lab Nat Prod, Serdang 43400, Malaysia

[2] Univ Putra Malaysia, Fac Sci, Dept Biol, Serdang 43400, Malaysia

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 07期

关键词：

D O I：

10.1021/np0500171

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new labdane diterpene glucoside, curcumanggoside (1), together with nine known compounds, including labda-8(17),12-diene-15,16-dial (2), calcaratarin A (3), zerumin B (4), scopoletin, demethoxycurcumin, bisdemethoxycurcumin, 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one, curcumin, and p-hydroxycinnamic acid, have been isolated from the rhizomes of Curcuma mangga. Their structures were determined using a combination of 1D (H-1 NMR, C-13 NMR, DEPT) and 2D (COSY, HSQC, HMBC) NMR techniques. All diarylheptanoids and scopoletin showed significant antioxidant activity. Zerumin B, demethoxycurcumin, bisdemethoxycurcumin, and curcumin also exhibited cytotoxic activity against a panel of five human tumor cell lines.

引用

页码：1090 / 1093

页数：4

共 25 条

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