The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection

被引：731

作者：

Patel, Swati G. ^{[1
,2
]}

Karlitz, Jordan J. ^{[3
]}

Yen, Timothy ^{[1
]}

Lieu, Christopher H. ^{[1
]}

Boland, C. Richard ^{[4
]}

机构：

[1] Univ Colorado, Anschutz Med Ctr, Aurora, CO 80045 USA

[2] Mt Reg Vet Affairs Med Ctr, Aurora, CO USA

[3] Denver Hlth Hosp Author, Denver, CO USA

[4] Univ Calif San Diego, San Diego, CA 92103 USA

来源：

LANCET GASTROENTEROLOGY & HEPATOLOGY | 2022年 / 7卷 / 03期

关键词：

SUSCEPTIBILITY GENE-MUTATIONS; YOUNG-ONSET; FAMILY-HISTORY; UNITED-STATES; TASK-FORCE; 1ST-DEGREE RELATIVES; MOLECULAR-FEATURES; LYNCH SYNDROME; FOLLOW-UP; ADULTS;

D O I：

10.1016/S2468-1253(21)00426-X

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

The incidence of early-onset colorectal cnacer-ie, colorectal cancer diagnosed in patients under the age of 50 years- has been increasing around the world. This Series paper provides a comprehensive review on the topic of early-onset colorectal cancer, including examining the epidemiology of early-onset colorectal cancer around the world, clinical and pathological features, genetic and epigenetic landscapes, and emerging data on the clinical risk factors associated with this malignancy. Evidence-based approaches to prevention and early detection are also presented.

引用

页码：262 / 274

页数：13

共 135 条

[1]

Colorectal cancer outcomes and treatment patterns in patients too young for average-risk screening [J].

Abdelsattar, Zaid M. ;

Wong, Sandra L. ;

Regenbogen, Scott E. ;

Jomaa, Diana M. ;

Hardiman, Karin M. ;

Hendren, Samantha .

CANCER, 2016, 122 (06) :929-934

[2]

Geographic and intra-racial disparities in early-onset colorectal cancer in the SEER 18 registries of the United States [J].

Abualkhair, Wesal H. ;

Zhou, Meijiao ;

Ochoa, Carolina O. ;

Lacayo, Leonel ;

Murphy, Caitlin ;

Wu, Xiao-Cheng ;

Karlitz, Jordan J. .

CANCER MEDICINE, 2020, 9 (23) :9150-9159

[3]

Allwell-Brown G, 2020, LANCET GLOB HEALTH, V8, pE799, DOI 10.1016/S2214-109X(20)30079-6

[4]

A High Degree of LINE-1 Hypomethylation Is a Unique Feature of Early-Onset Colorectal Cancer [J].

Antelo, Marina ;

Balaguer, Francesc ;

Shia, Jinru ;

Shen, Yan ;

Hur, Keun ;

Moreira, Leticia ;

Cuatrecasas, Miriam ;

Bujanda, Luis ;

Dolores Giraldez, Maria ;

Takahashi, Masanobu ;

Cabanne, Ana ;

Edmundo Barugel, Mario ;

Arnold, Mildred ;

Luis Roca, Enrique ;

Andreu, Montserrat ;

Castellvi-Bel, Sergi ;

Llor, Xavier ;

Jover, Rodrigo ;

Castells, Antoni ;

Boland, C. Richard ;

Goel, Ajay .

PLOS ONE, 2012, 7 (09)

[5]

CIMP Status of Interval Colon Cancers: Another Piece to the Puzzle [J].

Arain, Mustafa A. ;

Sawhney, Mandeep ;

Sheikh, Shehla ;

Anway, Ruth ;

Thyagarajan, Bharat ;

Bond, John H. ;

Shaukat, Aasma .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (05) :1189-1195

[6]

Cumulative Burden of Colorectal Cancer Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer [J].

Archambault, Alexi N. ;

Su, Yu-Ru ;

Jeon, Jihyoun ;

Thomas, Minta ;

Lin, Yi ;

Conti, David V. ;

Win, Aung Ko ;

Sakoda, Lori C. ;

Lansdorp-Vogelaar, Iris ;

Peterse, Elisabeth F. P. ;

Zauber, Ann G. ;

Duggan, David ;

Holowatyj, Andreana N. ;

Huyghe, Jeroen R. ;

Brenner, Hermann ;

Cotterchio, Michelle ;

Bezieau, Stephane ;

Schmit, Stephanie L. ;

Edlund, Christopher K. ;

Southey, Melissa C. ;

MacInnis, Robert J. ;

Campbell, Peter T. ;

Chang-Claude, Jenny ;

Slattery, Martha L. ;

Chan, Andrew T. ;

Joshi, Amit D. ;

Song, Mingyang ;

Cao, Yin ;

Woods, Michael O. ;

White, Emily ;

Weinstein, Stephanie J. ;

Ulrich, Cornelia M. ;

Hoffmeister, Michael ;

Bien, Stephanie A. ;

Harrison, Tabitha A. ;

Hampe, Jochen ;

Li, Christopher I. ;

Schafmayer, Clemens ;

Offit, Kenneth ;

Pharoah, Paul D. ;

Moreno, Victor ;

Lindblom, Annika ;

Wolk, Alicja ;

Wu, Anna H. ;

Li, Li ;

Gunter, Marc J. ;

Gsur, Andrea ;

Keku, Temitope O. ;

Pearlman, Rachel ;

Bishop, D. Timothy .

GASTROENTEROLOGY, 2020, 158 (05) :1274-+

[7]

Racial Disparities in Clinical Presentation and Survival Times Among Young-Onset Colorectal Adenocarcinoma [J].

Arshad, Hafiz Muhammad Sharjeel ;

Kabir, Christopher ;

Tetangco, Eula ;

Shah, Natahsa ;

Raddawi, Hareth .

DIGESTIVE DISEASES AND SCIENCES, 2017, 62 (09) :2526-2531

[8]

Cost-utility of colorectal cancer screening at 40 years old for average-risk patients [J].

Azad, Nilofer S. ;

Leeds, Ira L. ;

Wanjau, Waruguru ;

Shin, Eun J. ;

Padula, William, V .

PREVENTIVE MEDICINE, 2020, 133

[9]

Trends in Smoking Behaviors Among US Adolescent Cigarette Smokers [J].

Azagba, Sunday ;

Manzione, Lauren ;

Shan, Lingpeng ;

King, Jessica .

PEDIATRICS, 2020, 145 (03)

[10]

Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors [J].

Baba, Yoshifumi ;

Huttenhower, Curtis ;

Nosho, Katsuhiko ;

Tanaka, Noriko ;

Shima, Kaori ;

Hazra, Aditi ;

Schernhammer, Eva S. ;

Hunter, David J. ;

Giovannucci, Edward L. ;

Fuchs, Charles S. ;

Ogino, Shuji .

MOLECULAR CANCER, 2010, 9

← 1 2 3 4 5 6 7 8 9 10 →