High throughput screening methods for asymmetric synthesis

被引：11

作者：

Charbonneau, V ^{[1
]}

Ogilvie, WW ^{[1
]}

机构：

[1] Univ Ottawa, Dept Chem, Ottawa, ON K1N 6N5, Canada

来源：

MINI-REVIEWS IN ORGANIC CHEMISTRY | 2005年 / 2卷 / 04期

关键词：

high throughput screening; combinatorial chemistry; parallel synthesis; reaction screening; asymmetric reaction screening; enantioselective reaction screening;

D O I：

10.2174/157019305774322725

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Combinatorial and high throughput methods have recently been applied to chemical reaction development as it greatly increases the reactivity "space" available to the chemist. Recent focus has been the development of detection methods, particularly those directed towards enantioselectivity. Progress in this area has been reviewed with particular emphasis placed on recent enantioselective methods.

引用

页码：313 / 332

页数：20

共 128 条

[1] EMDee: An enzymatic method for determining enantiomeric excess [J].