Vic-triazolines .36. New synthesis of ethyl 1-alkyl-1,4,5,6-tetrahydro-6-oxopyridine-3-carboxylates and 1-alkyl-1,4,5,6-tetrahydro-6-oxopyridine-3-carbonitriles through reduction of N-2-nitroarylamidines

被引：4

作者：

Angelini, R ^{[1
]}

Erba, E ^{[1
]}

Pocar, D ^{[1
]}

机构：

[1] UNIV MILAN, FAC FARM, IST CHIM ORGAN, I-20133 MILAN, ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 08期

关键词：

D O I：

10.1039/p19960000837

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ethyl 1-alkyl-1,4-dihydropyridine-3-carboxylates 2a-d and 1-alkyl-1,4-dihydropyridine-3-carbonitriles 2e,f were allowed to react with 2-nitrophenyl azide 3 to give tertiary amidines 4 by spontaneous rearrangement of the triazoline cycloadducts. Ready catalytic hydrogenation with Pd-C of 4 gave the corresponding ethyl 1-alkyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylates 5a-d and 1-alkyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitriles 5e,f.

引用

页码：837 / 840

页数：4

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