Effect of potentially probiotic lactobacilli on faecal enzyme activity in minipigs on a high-fat, high-cholesterol diet - a preliminary in vivo trial

被引:45
作者
Haberer, P
du Toit, M
Dicks, LMT
Ahrens, F
Holzapfel, WH
机构
[1] Bundesforsch Anstalt Ernahrung, Inst Hyg & Toxikol BFE, D-76131 Karlsruhe, Germany
[2] Univ Stellenbosch, Dept Microbiol, ZA-7600 Stellenbosch, South Africa
[3] ISForsch Gesell Expt Tierphysiol & Tierernahrung, D-23812 Wahlstedt, Germany
关键词
probiotic; lactobacilli; beta-glucuronidase; azoreductase;
D O I
10.1016/S0168-1605(03)00076-X
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Minipigs were fed a "Western-style", high-cholesterol diet for a baseline period, followed by the diet containing a mixture of three Lactobacillus strains with potential probiotic features, after which a normal pig diet was followed. The faecal enzyme activity for beta-glucuronidase and azoreductase, which are commonly considered as markers for procarcinogenic activity, was significantly reduced during the 5 weeks of "probiotic" supplementation. During the period of Lactobacillus administration, the cell counts for total anaerobes increased, whereas the total number of aerobes showed no change. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:287 / 291
页数:5
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