Cloning and functional analysis of the gene encoding the 33- to 36-kilodalton outer membrane protein associated with carbapenem resistance in Acinetobacter baumannii
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作者:
Tomás, MDM
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Tomás, MDM
Beceiro, A
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Beceiro, A
Pérez, A
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Pérez, A
Velasco, D
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Velasco, D
Moure, R
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Moure, R
Villanueva, R
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Villanueva, R
Martínez-Beltrán, J
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Martínez-Beltrán, J
Bou, G
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机构:Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
Bou, G
机构:
[1] Unidad Invest, Microbiol Serv, La Coruna 15006, Spain
[2] Hosp Ramon & Cajal, Microbiol Serv, E-28034 Madrid, Spain
We investigated a multiresistant strain of Acinetobacter baumannii isolated in our hospital. Analysis of the N-terminal peptide sequence of the outer membrane proteins (OMPs) purified from the strain allowed us to clone and sequence the nucleotides of the gene encoding the 33- to 36-kDa OMP associated with carbapenem resistance in A. baumannii.