Electrophilic amination of hydrazones:: A new synthetic route to protected α-hydrazino- and α-aminoketones

被引：15

作者：

Enders, D ^{[1
]}

Joseph, R ^{[1
]}

Poiesz, C ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

TETRAHEDRON | 1998年 / 54卷 / 34期

关键词：

D O I：

10.1016/S0040-4020(98)00595-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-BOC protected alpha-hydrazinoketones 4 and N-tris protected alpha-aminoketones 6 were synthesized in good overall yields by deprotonation and electrophilic amination of the corresponding ketone-N,N-dimethylhydrazones 2 and subsequent oxidative cleavage of the resulting product hydrazones 3 and 5 by ozonolysis. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：10069 / 10078

页数：10

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