DNA damage checkpoint in budding yeast

被引：139

作者：

Longhese, MP ^{[1
]}

Foiani, M ^{[1
]}

Muzi-Falconi, M ^{[1
]}

Lucchini, G ^{[1
]}

Plevani, P ^{[1
]}

机构：

[1] Dipartimento Genet & Biol Microrganismi, I-20133 Milan, Italy

来源：

EMBO JOURNAL | 1998年 / 17卷 / 19期

关键词：

budding yeast; cell cycle; checkpoints; DNA damage; DNA replication;

D O I：

10.1093/emboj/17.19.5525

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Eukaryotic cells have evolved a network of control mechanisms, known as checkpoints, which coordinate cell-cycle progression in response to internal and external cues. The yeast Saccharomyces cerevisiae has been invaluable in dissecting genetically the DNA damage checkpoint pathway. Recent results on posttranslational modifications and protein-protein interactions of some key factors provide new insights into the architecture of checkpoint protein complexes and their order of function.

引用

页码：5525 / 5528

页数：4

共 29 条

[1] A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription
Aboussekhra, A
Vialard, JE
Morrison, DE
delaTorreRuiz, MA
Cernakova, L
Fabre, F
Lowndes, NF
[J]. EMBO JOURNAL, 1996, 15 (15) : 3912 - 3922
[2] The Schizosaccharomyces pombe rad3 checkpoint gene
Bentley, NJ
Holtzman, DA
Flaggs, G
Keegan, KS
DeMaggio, A
Ford, JC
Hoekstra, M
Carr, AM
[J]. EMBO JOURNAL, 1996, 15 (23) : 6641 - 6651
[3] The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast
Brush, GS
Morrow, DM
Hieter, P
Kelly, TJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (26) : 15075 - 15080
[4] Control of cell cycle arrest by the Mec1(sc)/Rad3(sp) DNA structure checkpoint pathway
Carr, AM
[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1997, 7 (01) : 93 - 98
[5] The anaphase inhibitor of Saccharomyces cerevisiae Pds1p is a target of the DNA damage checkpoint pathway
Cohen-Fix, O
Koshland, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (26) : 14361 - 14366
[6] RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation
de la Torre-Ruiz, MA
Green, CM
Lowndes, NF
[J]. EMBO JOURNAL, 1998, 17 (09) : 2687 - 2698
[7] Cell cycle checkpoints: Preventing an identity crisis
Elledge, SJ
[J]. SCIENCE, 1996, 274 (5293) : 1664 - 1672
[8] CHECKPOINTS - CONTROLS THAT ENSURE THE ORDER OF CELL-CYCLE EVENTS
HARTWELL, LH
WEINERT, TA
[J]. SCIENCE, 1989, 246 (4930) : 629 - 634
[9] CELL-CYCLE CONTROL AND CANCER
HARTWELL, LH
KASTAN, MB
[J]. SCIENCE, 1994, 266 (5192) : 1821 - 1828
[10] Distinct roles of yeast MEC and RAD checkpoint genes in transcriptional induction after DNA damage and implications for function
Kiser, GL
Weinert, TA
[J]. MOLECULAR BIOLOGY OF THE CELL, 1996, 7 (05) : 703 - 718

← 1 2 3 →