On the determination of bioequivalence

被引：22

作者：

Farolfi, M

Powers, JD

Rescigno, A

机构：

[1] Childrens Hosp, Res Fdn, Columbus, OH 43205 USA

[2] Solarolo, Mantova, Italy

[3] Univ Minnesota, Coll Pharm, Minneapolis, MN 55082 USA

来源：

PHARMACOLOGICAL RESEARCH | 1999年 / 39卷 / 01期

关键词：

bioequivalence; area under the curve; maximum concentration; rate of absorption; extent of absorption;

D O I：

10.1006/phrs.1998.0405

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

The characteristics and advantages of a new method for the determination of bioequivalence are described. This method does not employ AUC or C-max, therefore it does not depend on a number of assumptions usually needed for the validity of the traditional method. (C) 1999 The Italian Pharmacological Society.

引用

页码：1 / 4

页数：4

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ALEXANDROV AD, 1965, MATH ITS CONTENT MET

[2]

ASYMPTOTIC FORMS OF TRACER CLEARANCE CURVES - THEORY AND APPLICATIONS OF IMPROVED EXTRAPOLATIONS [J].