A new method for the synthesis of nitrogen heterocycles via palladium catalyzed intramolecular hydroamination of allenes

被引：123

作者：

Meguro, M ^{[1
]}

Yamamoto, Y ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Sendai, Miyagi 9808578, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 30期

基金：

日本学术振兴会;

关键词：

allenes; cyclization; palladium; nitrogen heterocycles;

D O I：

10.1016/S0040-4039(98)01044-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The intramolecular hydroamination of certain allenes, bearing amine or sulfonyl amide groups at the terminus of the carbon chain, proceeded smoothly in the presence of catalytic amounts of palladium complex ( [(eta(3)-C3H5)PdCl](2)-dppf) under weakly acidic conditions ( 0.15-1.0 equivalent of acetic acid) to give the corresponding 2-vinylpyrrolidines and 2-vinylpiperidines in good to high yield. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5421 / 5424

页数：4

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