Pharmacokinetics using fluorine NMR in vivo

被引：55

作者：

Bachert, P ^{[1
]}

机构：

[1] Deutsch Krebsforschungszentrum, Abt Med Phys & Biophys, Forsch Schwerpunkt Radiol Diagnost & Therapie, D-60120 Heidelberg, Germany

来源：

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | 1998年 / 33卷

关键词：

fluorine; in vivo F-19 NMR spectroscopy; chemical-shift imaging; double resonance; dynamic nuclear polarization; nuclear Overhauser effect; spin decoupling; 5-fluorouracil; alpha-fluoro-beta-alanine; metabolism; pharmacokinetics; kinetic modeling; nonlinear compartment model; drug monitoring; chemotherapy; liver tumor;

D O I：

10.1016/S0079-6565(98)00016-8

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1 / 56

页数：56

共 186 条

[1]

ABRAGAM A, 1958, CR HEBD ACAD SCI, V246, P2253

[2] MAPPING OF METABOLITES IN WHOLE ANIMALS BY P-31 NMR USING SURFACE COILS [J].

ACKERMAN, JJH ;

GROVE, TH ;

WONG, GG ;

GADIAN, DG ;

RADDA, GK .

NATURE, 1980, 283 (5743) :167-170

[3]

ALBERT MS, 1994, NATURE, V370, P199, DOI 10.1038/370199a0

[4]

ALGER JR, 1981, SCIENCE, V214, P660, DOI 10.1126/science.7292005

[5]

[Anonymous], 1989, NUCL OVERHAUSER EFFE, DOI DOI 10.1002/MRC.1260280819

[6]

ARELLANO M, 1994, 2 ANN SCI M SOC MAGN, P1355

[7]

ARELLANO M, 1994, 2 ANN SCI M SOC MAGN, P1320

[8] PHARMACOKINETICS OF THE C-13 LABELED ANTICANCER AGENT TEMOZOLOMIDE DETECTED IN-VIVO BY SELECTIVE CROSS-POLARIZATION TRANSFER [J].

ARTEMOV, D ;

BHUJWALLA, ZM ;

MAXWELL, RJ ;

GRIFFITHS, JR ;

JUDSON, IR ;

LEACH, MO ;

GLICKSON, JD .

MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (03) :338-342

[9] Nuclear magnetic resonance imaging of airways in humans with use of hyperpolarized He-3 [J].

Bachert, P ;

Schad, LR ;

Bock, M ;

Knopp, MV ;

Ebert, M ;

Grossmann, T ;

Heil, W ;

Hofmann, D ;

Surkau, R ;

Otten, EW .

MAGNETIC RESONANCE IN MEDICINE, 1996, 36 (02) :192-196

[10] INVIVO H-1, P-31-(H-1) AND C-13-(H-1) MAGNETIC-RESONANCE SPECTROSCOPY OF MALIGNANT HISTIOCYTOMA AND SKELETAL-MUSCLE TISSUE IN MAN [J].

BACHERT, P ;

BELLEMANN, ME ;

LAYER, G ;

KOCH, T ;

SEMMLER, W ;

LORENZ, WJ .

NMR IN BIOMEDICINE, 1992, 5 (04) :161-170

← 1 2 3 4 5 6 7 8 9 10 →