Pathogens Resistant to Antibacterial Agents

被引：9

作者：

Chen, Luke F. ^{[1
]}

Chopra, Teena ^{[2
,3
]}

Kaye, Keith S. ^{[3
]}

机构：

[1] Duke Univ, Div Infect Dis & Int Hlth, Dept Med, Med Ctr, Durham, NC 27710 USA

[2] Harper Grace Hosp, Detroit Med Ctr, Dept Med, Div Infect Dis, Detroit, MI 48201 USA

[3] Wayne State Univ, Detroit, MI 48201 USA

来源：

MEDICAL CLINICS OF NORTH AMERICA | 2011年 / 95卷 / 04期

关键词：

Drug resistance; Methicillin-resistant Staphylococcus aureus; Vancomycin-resistant Enterococcus; Vancomycin intermediate-susceptible Staphylococcus aureus; Extended-spectrum beta-lactamase; Penicillin-resistant Streptococcus pneumoniae; Klebsiella pneumoniae carbapenemase; Acinetobacter baumanii; SPECTRUM BETA-LACTAMASE; PENICILLIN-BINDING PROTEINS; CASSETTE CHROMOSOME MEC; ENTERICA SEROTYPE TYPHI; MULTIRESISTANT ACINETOBACTER-BAUMANNII; INCREASING CEFTRIAXONE RESISTANCE; MINIMUM INHIBITORY CONCENTRATION; CAMPYLOBACTER-JEJUNI INFECTIONS; RESPIRATORY-TRACT PATHOGENS; BLOOD-STREAM INFECTION;

D O I：

10.1016/j.mcna.2011.03.005

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Resistance to antimicrobial drugs is increasing at an alarming rate among both gram-positive and gram-negative bacteria. Traditionally, bacteria resistant to multiple antimicrobial agents have been restricted to the nosocomial environment. A disturbing trend has been the recent emergence and spread of resistant pathogens in nursing homes, in the community, and in the hospital. This article reviews the epidemiology, molecular mechanisms of resistance, and treatment options for pathogens resistant to antimicrobial drugs.

引用

页码：647 / +

页数：31

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