Insulin, glucose and the increased risk of cancer in patients with type 2 diabetes

被引：31

作者：

Johnson, J. A. ^{[1
]}

Pollak, M. ^{[2
]}

机构：

[1] Univ Alberta, Sch Publ Hlth, Ctr Hlth Res Innovat, Edmonton, AB T6G 2E1, Canada

[2] McGill Univ, Dept Oncol, Montreal, PQ, Canada

来源：

DIABETOLOGIA | 2010年 / 53卷 / 10期

基金：

加拿大健康研究院;

关键词：

COLORECTAL-CANCER; BLOOD-GLUCOSE; RECEPTOR ISOFORM; C-PEPTIDE; GROWTH; METFORMIN; CELLS; COMPLICATIONS; THERAPIES; MORTALITY;

D O I：

10.1007/s00125-010-1855-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2086 / 2088

页数：3

共 32 条

[1] Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase [J].

Algire, Carolyn ;

Amrein, Lilian ;

Zakikhani, Mahvash ;

Panasci, Lawrence ;

Pollak, Michael .

[2] Glucose-lowering agents and cancer mortality rates in type 2 diabetes: assessing effects of time-varying exposure [J].

Bowker, S. L. ;

Yasui, Y. ;

Veugelers, P. ;

Johnson, J. A. .

DIABETOLOGIA, 2010, 53 (08) :1631-1637

[3] Increased cancer-related mortality for patients with type 2 diabetes who use sulforrylureas or insulin [J].

Bowker, SL ;

Majumdar, SR ;

Veugelers, P ;

Johnson, JA .

DIABETES CARE, 2006, 29 (02) :254-258

[4] Potential of Peroxisome Proliferator-Activated Receptor Gamma Antagonist Compounds as Therapeutic Agents for a Wide Range of Cancer Types [J].

Burton, Jack D. ;

Goldenberg, David M. ;

Blumenthal, Rosalyn D. .

PPAR RESEARCH, 2008, 2008

[5]

CARSTENSEN B, 2010, DIABETES IN PRESS

[6] The influence of glucose-lowering therapies on cancer risk in type 2 diabetes [J].

Currie, C. J. ;

Poole, C. D. ;

Gale, E. A. M. .

DIABETOLOGIA, 2009, 52 (09) :1766-1777

[7] Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells [J].

Dowling, Ryan J. O. ;

Zakikhani, Mahvash ;

Fantus, I. George ;

Pollak, Michael ;

Sonenberg, Nahum .

CANCER RESEARCH, 2007, 67 (22) :10804-10812

[8] Metformin and reduced risk of cancer in diabetic patients [J].

Evans, JMM ;

Donnelly, LA ;

Emslie-Smith, AM ;

Alessi, DR ;

Morris, AD .

BMJ-BRITISH MEDICAL JOURNAL, 2005, 330 (7503) :1304-1305

[9] Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells [J].

Frasca, F ;

Pandini, C ;

Scalia, P ;

Sciacca, L ;

Mineo, R ;

Costantino, A ;

Goldfine, ID ;

Belfiore, A ;

Vigneri, R .

MOLECULAR AND CELLULAR BIOLOGY, 1999, 19 (05) :3278-3288

[10] Does Insulin Therapy Promote, Reduce, or Have a Neutral Effect on Cancers? [J].

Gerstein, Hertzel C. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (05) :446-447

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