Ataxin-1 regulators in the spotlight

被引：4

作者：

Heintz, N ^{[1
]}

机构：

[1] Rockefeller Univ, Dept Mol Biol, New York, NY 10021 USA

来源：

SCIENCE | 2003年 / 301卷 / 5629期

关键词：

D O I：

10.1126/science.1086311

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：59 / 60

页数：2

共 8 条

[1] Huntingtin aggregation and toxicity in Huntington's disease [J].

Bates, G .

LANCET, 2003, 361 (9369) :1642-1644

[2] Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1 [J].

Chen, HK ;

Fernandez-Funez, P ;

Acevedo, SF ;

Lam, YC ;

Kaytor, MD ;

Fernandez, MH ;

Aitken, A ;

Skoulakis, EMC ;

Orr, HT ;

Botas, J ;

Zoghbi, HY .

CELL, 2003, 113 (04) :457-468

[3] Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice [J].

Emamian, ES ;

Kaytor, MD ;

Duvick, LA ;

Zu, T ;

Tousey, SK ;

Zoghbi, HY ;

Clark, HB ;

Orr, HT .

NEURON, 2003, 38 (03) :375-387

[4] Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy [J].

Katsuno, M ;

Adachi, H ;

Doyu, M ;

Minamiyama, M ;

Sang, C ;

Kobayashi, Y ;

Inukai, A ;

Sobue, G .

NATURE MEDICINE, 2003, 9 (06) :768-773

[5] Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy [J].

Katsuno, M ;

Adachi, H ;

Kume, A ;

Li, M ;

Nakagomi, Y ;

Niwa, H ;

Sang, C ;

Kobayashi, Y ;

Doyu, M ;

Sobue, G .

NEURON, 2002, 35 (05) :843-854

[6] 14-3-3 proteins in Lewy bodies in Parkinson disease and diffuse Lewy body disease brains [J].

Kawamoto, Y ;

Akiguchi, I ;

Nakamura, S ;

Honjyo, Y ;

Shibasaki, H ;

Budka, H .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2002, 61 (03) :245-253

[7] Neurofibrillary tangles of Alzheimer's disease brains contain 14-3-3 proteins [J].

Layfield, R ;

Fergusson, J ;

Aitken, A ;

Lowe, J ;

Landon, M ;

Mayer, RJ .

NEUROSCIENCE LETTERS, 1996, 209 (01) :57-60

[8] Beyond the Qs in the polyglutamine diseases [J].

Orr, HT .

GENES & DEVELOPMENT, 2001, 15 (08) :925-932

← 1 →