Natural feruloyl monoglyceride macrocycles as protecting factors against free-radical damage of lipidic membranes

被引：9

作者：

D'Abrosca, Brigida ^{[1
]}

Fiorentino, Antonio ^{[1
]}

Pacifico, Severina ^{[1
]}

Cefarelli, Giuseppe ^{[1
]}

Uzzo, Piera ^{[1
]}

Letizia, Marianna ^{[1
]}

Monaco, Pietro ^{[1
]}

机构：

[1] Univ Naples 2, Dipartimento Sci Vita, I-81100 Caserta, Italy

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2007年 / 17卷 / 15期

关键词：

feruloyl monoglyceride macrocycles; Carex distachya; lipidic membranes; antioxidant activity; spectroscopic analysis;

D O I：

10.1016/j.bmcl.2007.05.047

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Nine novel natural feruloyl monoglyceride (MGs) macrocycles have been isolated from the leaves of Carex distachya, an herbaceous plant growing in the Mediterranean maquis. All the structures have been elucidated on the basis of their spectroscopic features, especially two-dimensional NMR (DQ-COSY, TOCSY, NOESY, ROESY, HSQC, HMBC, HSQC-TOCSY) and ESI-MS. All the compounds have been assayed as protecting factors against the radical damage of the lipids by using different antioxidant tests. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：4135 / 4139

页数：5

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