2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

被引：1404

作者：

Heidenreich, Paul A. ^{[1
,2
]}

Bozkurt, Biykem ^{[3
,4
,5
,6
,7
]}

Aguilar, David ^{[8
]}

Allen, Larry A. ^{[9
]}

Byun, Joni J.

Colvin, Monica M. ^{[10
,11
]}

Deswal, Anita ^{[12
,13
]}

Drazner, Mark H. ^{[14
]}

Dunlay, Shannon M. ^{[15
]}

Evers, Linda R. ^{[16
,17
]}

Fang, James C. ^{[18
]}

Fedson, Savitri E. ^{[19
]}

Fonarow, Gregg C. ^{[20
,21
]}

Hayek, Salim S. ^{[22
]}

Hernandez, Adrian F. ^{[23
]}

Khazanie, Prateeti ^{[24
]}

Kittleson, Michelle M. ^{[25
]}

Lee, Christopher S. ^{[26
]}

Link, Mark S. ^{[27
,28
,29
]}

Milano, Carmelo A. ^{[30
]}

Nnacheta, Lorraine C. ^{[31
]}

Sandhu, Alexander T. ^{[32
]}

Stevenson, Lynne Warner ^{[33
,34
]}

Vardeny, Orly ^{[35
,36
]}

Vest, Amanda R. ^{[37
]}

Yancy, Clyde W. ^{[38
,39
,40
,41
,42
,43
]}

机构：

[1] Stanford Univ, Sch Med, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Med, Qual, Stanford, CA 94305 USA

[3] Baylor Coll Med, Houston, TX 77030 USA

[4] DeBakey VA Med Ctr, Dept Cardiol, Houston, TX USA

[5] DeBakey VA Med Ctr, Houston, TX USA

[6] Winters Ctr Heart Failure Res, Houston, TX USA

[7] Cardiovasc Res Inst, Houston, TX USA

[8] Univ Kentucky, Med, Dept Med, Div Cardiovasc Med, Lexington, KY 40506 USA

[9] Univ Colorado, Sch Med, Med, Dept Med,Div Cardiol, Anschutz Med Campus, Boulder, CO 80309 USA

[10] Univ Michigan, Dept Med, Cardiovasc Div, Med, Ann Arbor, MI 48109 USA

[11] Univ Michigan, Heart Transplant Program, Adv Heart Failure Transplant & MCS Natera, Ann Arbor, MI 48109 USA

[12] UT MD Anderson Canc Ctr, Med, Houston, TX USA

[13] UT MD Anderson Canc Ctr, Cardiol, Houston, TX USA

[14] UT Southwestern Med Ctr, Cardiol, Dept Internal Med, Houston, TX USA

[15] Mayo Clin, Hlth Serv Res & Med, Dept Cardiovasc Med, Rochester, NY USA

[16] Stevens Lee Shareholder, Allentown, PA USA

[17] Stevens & Lees Energy Commun & Publ Util Grp, Allentown, PA USA

[18] Univ Utah, Med, Div Cardiovasc Med, Salt Lake City, UT 84112 USA

[19] Michael E DeBakey Med Ctr, Adv Heart Failure & Transplantat, Sect Cardiol, Houston, TX USA

[20] Univ Calif Los Angeles, Geffen Sch Med, Cardiovasc Med, Los Angeles, CA 90024 USA

[21] Univ Calif Los Angeles, Div Cardiol, Dept Med, Los Angeles, CA 90024 USA

[22] Univ Michigan, Dept Med, Div Cardiol, Ann Arbor, MI 48109 USA

[23] Duke Univ, Sch Med, Clin Res, Durham, NC 27706 USA

[24] Univ Colorado, Med, Dept Med, Div Cardiol, Boulder, CO 80309 USA

[25] Smidt Heart Inst Cedars Sinai, Med, Cardiol, Los Angeles, CA USA

[26] Boston Coll, William F Connell Sch Nursing, Res, Chestnut Hill, MA 02167 USA

[27] UT Southwestern Med Ctr, Med, Dallas, TX USA

[28] UT Southwestern Med Ctr, Cardiac Elect, Dallas, TX USA

[29] UT Southwestern Med Ctr, Heart Dis, Dept Internal Med, Div Cardiol, Dallas, TX USA

[30] Duke Univ, Med Ctr, Surg, Surg Dept, Durham, NC 27706 USA

[31] Amer Heart Assoc, Amer Coll Cardiol, Dallas, TX USA

[32] Stanford Univ, Med, Div Cardiol, Dept Med, Stanford, CA 94305 USA

[33] Vanderbilt Univ Sch Med, Vanderbilt Heart & Vasc Inst, Cardiomyopathy, Nashville, TN USA

[34] Vanderbilt Univ Sch Med, Vanderbilt Heart & Vasc Inst, Cardiovasc Med, Nashville, TN USA

[35] Minneapolis VA Hlth Care Syst, Minneapolis, MN USA

[36] Univ Minnesota, Med, Dept Med, Minneapolis, MN 55455 USA

[37] Tufts Med Ctr, Cardiovasc Ctr, Med, Boston, MA 02111 USA

[38] Northwestern Univ, Feinberg Sch Med, Evanston, IL 60208 USA

[39] Northwestern Mem Hosp, Med Cardiol, Evanston, IL USA

[40] Northwestern Mem Hosp, Med Social Sci, Evanston, IL USA

[41] Northwestern Mem Hosp, Cardiol, Evanston, IL USA

[42] Northwestern Mem Hosp, Div & Inclus, Evanston, IL USA

[43] Northwestern Mem Hosp, Cardiovasc Inst Internal Med Cardiol & Med Social, Evanston, IL USA

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2022年 / 79卷 / 17期

关键词：

ACC/AHA Clinical Practice Guidelines; heart failure; heart failure with reduced ejection fraction; heart failure with; preserved ejection fraction; heart failure with mildly reduced ejection fraction; systolic heart failure; heart failure rehabilitation; cardiac failure; chronic heart failure; acute decompensated heart failure; cardiogenic shock; beta blockers; mineralocorticoid receptor antagonists; ACE inhibitors; angiotensin and neprilysin receptor antagonist; sacubitril-valsartan; angiotensin receptor antagonist; sodium glucose co-transporter 2; SGLT2; inhibitors; cardiac amyloidosis; atrial fibrillation; congestive heart failure; guideline-directed medical therapy; diabetes; cardiomyopathy; valvular heart disease; mitral regurgitation; cardiomyopathy in pregnancy; reduced ejection fraction; right heart pressure; palliative care; cardio-oncology; social determinants of health; CARDIAC-RESYNCHRONIZATION THERAPY; LEFT-VENTRICULAR DYSFUNCTION; QUALITY-OF-LIFE; PRESERVED EJECTION FRACTION; ACUTE MYOCARDIAL-INFARCTION; CARDIOVASCULAR MAGNETIC-RESONANCE; MECHANICAL CIRCULATORY SUPPORT; BRAIN NATRIURETIC PEPTIDE; CORONARY-ARTERY-DISEASE; FUNCTIONAL MITRAL REGURGITATION;

D O I：

10.1016/j.jacc.2021.12.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

AIM The "2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure" replaces the "2013 ACCF/AHA Guideline for the Management of Heart Failure" and the "2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure." The 2022 guideline is intended to provide patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure. METHODS A comprehensive literature search was conducted from May 2020 to December 2020, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from MEDLINE (PubMed), EMBASE, the Cochrane Collaboration, the Agency for Healthcare Research and Quality, and other relevant databases. Additional relevant clinical trials and research studies, published through September 2021, were also considered. This guideline was harmonized with other American Heart Association/American College of Cardiology guidelines published through December 2021. STRUCTURE Heart failure remains a leading cause of morbidity and mortality globally. The 2022 heart failure guideline provides recommendations based on contemporary evidence for the treatment of these patients. The recommendations present an evidencebased approach to managing patients with heart failure, with the intent to improve quality of care and align with patients' interests. Many recommendations from the earlier heart failure guidelines have been updated with new evidence, and new recommendations have been created when supported by published data. Value statements are provided for certain treatments with high-quality published economic analyses.

引用

页码：E253 / E421

页数：159

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