An Escherichia coli gene responsive to heavy metals

被引：20

作者：

Babai, R ^{[1
]}

Ron, EZ ^{[1
]}

机构：

[1] Tel Aviv Univ, Dept Mol Microbiol & Biotechnol, IL-69978 Tel Aviv, Israel

来源：

FEMS MICROBIOLOGY LETTERS | 1998年 / 167卷 / 02期

关键词：

heavy metal; cadmium; mercury; zinc; stress response; gene regulation;

D O I：

10.1111/j.1574-6968.1998.tb13215.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Using in vivo translational gene fusion in Escherichia coli K-12 we identified a gene that is specifically induced by heavy metals, cadmium, mercury and zinc, at nmolar concentrations. This gene was identified by homology to known zinc and cadmium transporters. We created a disruption of the gene that resulted only in a minor increase in sensitivity to cadmium, suggesting that the fusion, which is at the carboxy-terminal end of the molecule, probably allows for at least partial activity of. the protein. (C) 1998 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：107 / 111

页数：5