A novel symmetric sulfur-containing biscembranoid from the Formosan soft coral Sinularia flexibilis

被引：41

作者：

Chen, Bo-Wei ^{[1
]}

Chao, Chih-Hua ^{[1
]}

Su, Jui-Hsin ^{[2
]}

Huang, Chiung-Yao ^{[1
]}

Dai, Chang-Feng ^{[3
]}

Wen, Zhi-Hong ^{[1
,4
]}

Sheu, Jyh-Horng ^{[1
,4
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 804, Taiwan

[2] Natl Museum Marine Biol & Aquarium, Taiwan Coral Res Ctr, Checheng 944, Pingtung, Taiwan

[3] Natl Taiwan Univ, Inst Oceanog, Taipei 112, Taiwan

[4] Natl Sun Yat Sen Univ, Asia Pacific Ocean Res Ctr, Kaohsiung 804, Taiwan

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 44期

关键词：

Soft coral; Sinularia flexibilis; Thioflexibilolide A; Anti-inflammatory activity; Neuroprotective activity; TERPENOIDS; LOCHMODES;

D O I：

10.1016/j.tetlet.2010.08.027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A structurally unique symmetric sulfur-containing biscembranoid, namely, thioflexibilolide A (1), was isolated from the soft coral Sinularia flexibilis. The structure was determined by extensive spectroscopic analyses. Compound 1 has been found to possess significant anti-inflammatory and neuroprotective activities. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：5764 / 5766

页数：3

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