1,4,7-triazacyclononane-1-succinic acid-4,7-diacetic acid (NODASA):: a new bifunctional chelator for radio gallium-labelling of biomolecules

被引：79

作者：

André, JP

Maecke, HR

Zehnder, M

Macko, L

Akyel, KG

机构：

[1] Univ Basel Hosp, Inst Nucl Med, Div Radiol Chem, CH-4031 Basel, Switzerland

[2] Univ Minho, Dept Chem, Braga, Portugal

[3] Univ Basel, Inst Inorgan Chem, Basel, Switzerland

[4] Navartis Pharma AG, Basel, Switzerland

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 12期

关键词：

D O I：

10.1039/a801294f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new bifunctional chelator NODASA (1,4,7-triazacyclononane-1-succinic acid-4,7-diacetic acid) has been synthesised, its kinetically inert gallium(III) complex was crystallographically characterized and conjugated to a model aminoacidamide showing the feasibility of a prelabelling approach with Ga-68,Ga-67.

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页码：1301 / 1302

页数：2

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