High prevalence of vitamin D deficiency in urban health checkup population

被引：95

作者：

Ning, Zhiwei ^{[1
]}

Song, Shufan ^{[2
]}

Miao, Li ^{[1
]}

Zhang, Pengrui ^{[1
]}

Wang, Xin ^{[3
]}

Liu, Jia ^{[1
]}

Hu, Yanjin ^{[1
]}

Xu, Yuan ^{[1
]}

Zhao, Tingting ^{[4
]}

Liang, Yufang ^{[4
]}

Wang, Qingtao ^{[4
]}

Liu, Lihong ^{[5
]}

Zhang, Jing ^{[6
]}

Hu, Lizhi ^{[6
]}

Huo, Mingyan ^{[7
]}

Zhou, Qinyun ^{[7
]}

机构：

[1] Capital Med Univ, Beijing Chaoyang Hosp, Dept Endocrinol & Metab, Beijing 100020, Peoples R China

[2] Capital Med Univ, Beijing Chaoyang Hosp, Dept Infect Dis & Clin Microbiol, Beijing 100020, Peoples R China

[3] ACURE Biotechnol Inc, 8780 Manahan Dr, Ellicott City, MD 21043 USA

[4] Capital Med Univ, Beijing Chaoyang Hosp, Dept Lab Med, Beijing 100020, Peoples R China

[5] Capital Med Univ, Beijing Chaoyang Hosp, Dept Pharm, Beijing 100020, Peoples R China

[6] Tianjin Med Univ, Basic Med Sch, Tianjin 300070, Peoples R China

[7] Chengde Med Coll, Affiliate Hosp, Chengde 67000, Hebei Province, Peoples R China

来源：

CLINICAL NUTRITION | 2016年 / 35卷 / 04期

关键词：

Vitamin D; 25-hydroxy vitamin D; Vitamin D deficiency; Prevalence; Season; Chinese; ADOLESCENT GIRLS; BONE TURNOVER; UNITED-STATES; WOMEN; GUIDELINE;

D O I：

10.1016/j.clnu.2015.05.019

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

Background: Vitamin D deficiency is documented as a common health problem in the world. Limited data has been found on the prevalence of vitamin D deficiency in Beijing area. Aim: To investigate the prevalence s of vitamin D deficiency in urban Beijing residents and the seasonal and monthly serum 25(OH)D variation in this population. Methods: This is an urban hospital based cross-sectional study lasting whole 2 years. 5531 (5-101 years old) urban Beijing residents for health checkup are recruited from December 9th, 2011 to December 8th, 2013. Each subject completed a questionnaire designed to quantify intake of vitamin D through food, vitamin D supplements, hours of sun exposure, sunscreen use over the past month. Serum 25(OH)D is statistically analyzed in accordance with gender, age, and time-lines. Results: Vitamin D deficiency (Serum 25(OH)D level <= 20 ng/mL) and sever deficiency (Serum 25(OH)D level <= 10 ng/mL) are highly prevalent in this population. The prevalence of vitamin D deficiency is 87.1% and higher prevalence is found in female (89.0%) than male (84.9% P < 0.001). Severe vitamin D deficiency is also higher in female than male (59.3% and 42.7%, respectively, P < 0.001). Female under 20 and over 80 have lower 25(OH)D levels compared to 40-60 years old female (both P < 0.05). Severe vitamin D deficiency are also highly prevalence in this two group (60.9% and 54.1%) compared with 40-60 years old females (43.1%, both P < 0.05). Seasonal variation are also found in this population (P < 0.01). Autumn and summer have the higher 25(OH)D level than winter and spring in both genders (P < 0.001). Winter and spring have higher vitamin D deficiency and Severe deficiency than the other two seasons (P < 0.05). Serum 25(OH)D level peaks in Octolier and troughed in April in both female and male. Lower serum 25(OH)D level are found in April than February (P < 0.05) in both gender. Conclusions: This is the first time to examine the prevalence of vitamin D deficiency among urban Beijing residents spanning the age spectrum. And Vitamin D deficiency and severe deficiency is found highly prevalent in this population, especially among females under 20 and older than 80 and in winter and spring seasons. Targeted prevention on vitamin D deficiency is urgent for this population. (C) 2015 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

引用

页码：859 / 863

页数：5

共 25 条

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Total Vitamin D Assay Comparison of the Roche Diagnostics "Vitamin D Total" Electrochemiluminescence Protein Binding Assay with the Chromsystems HPLC Method in a Population with both D2 and D3 forms of Vitamin D [J].