Layer-by-layer biosensor assembly incorporating functionalized quantum dots

被引：109

作者：

Constantine, CA

Gattás-Asfura, KM

Mello, SV

Crespo, G

Rastogi, V

Cheng, TC

DeFrank, JJ

Leblanc, RM

机构：

[1] Univ Miami, Dept Chem, Coral Gables, FL 33146 USA

[2] USA, Edgewood Chem Biol Ctr, Biotechnol Team, Res & Technol Directorate, Aberdeen Proving Ground, MD 21010 USA

来源：

LANGMUIR | 2003年 / 19卷 / 23期

关键词：

D O I：

10.1021/la035237y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Layer-by-layer (LbL) assembly has been utilized to fabricate an ultrathin film of polyelectrolytes. The architecture was composed of chitosan and organophosphorus hydrolase polycations along with thioglycolic acid-capped CdSe quantum dots (QDs) as the polyanion. The topography of the films was studied using epifluorescence microscopy imaging. The photoluminescence property of the functionalized QDs improved when sandwiched between the polycation layers. The enhanced optical property of QDs allowed easy monitoring of LbL growth and detection of paraoxon with high sensitivity. The presence of organophosphorus compounds was confirmed through UV-vis and emission spectroscopies.

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收藏

页码：9863 / 9867

页数：5

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