Sclerotigenin:: A new antiinsectan benzodiazepine from the sclerotia of Penicillium sclerotigenum

被引：71

作者：

Joshi, BK

Gloer, JB ^{[1
]}

Wicklow, DT

Dowd, PF

机构：

[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA

[2] USDA ARS, Natl Ctr Agr Utilizat Res, Bioact Agents Res Unit, Peoria, IL 61604 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 04期

关键词：

D O I：

10.1021/np980511n

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new benzodiazepine, sclerotigenin (1), was isolated from organic extracts of the sclerotia of Penicillium sclerotigenum (NRRL 3461) along with two known griseofulvin analogues. The structure of 1 was determined primarily by analysis of H-1 NMR, C-13 NMR, HMQC, and HMBC data. Compound 1 was the major component of the CH2Cl2 extract of P. sclerotigenum sclerotia and is responsible for most of the antiinsectan activity of the extract against the crop pest Helicoverpa tea.

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页码：650 / 652

页数：3

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