Induction of apoptosis in HEp-2 cells by infection with herpes simplex virus type 2

被引：40

作者：

Koyama, AH ^{[1
]}

Akari, H

Adachi, A

Goshima, F

Nishiyama, Y

机构：

[1] Univ Tokushima, Sch Med, Dept Virol, Tokushima 7708503, Japan

[2] Nagoya Univ, Sch Med, Dis Mechanism & Control Res Inst, Virol Lab, Nagoya, Aichi 4668550, Japan

来源：

ARCHIVES OF VIROLOGY | 1998年 / 143卷 / 12期

关键词：

D O I：

10.1007/s007050050473

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Although herpes simplex virus type 1 (HSV-I) does not induce apoptosis in infected HEp-2 cells, herpes simplex virus type 2 (HSV-2) did induce apoptosis in a small but significant fraction of the same cells. Apoptosis was not observed in Vero or HeLa cells infected with HSV-2. In addition, HSV-2 infection in the presence of cycloheximide induced extensive apoptosis of HEp-2 or HeLa cells.

引用

页码：2435 / 2441

页数：7

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