Receptor null mice reveal contrasting roles for estrogen receptor α and β in reproductive tissues

被引:115
作者
Couse, JF [1 ]
Hewitt, SC [1 ]
Korach, KS [1 ]
机构
[1] NIEHS, Receptor Biol Sect, Reprod & Dev Toxicol Lab, NIH, Res Triangle Pk, NC 27709 USA
关键词
estrogen receptor; estrogen insensitivity; uterus; ovary; testis; mammary gland;
D O I
10.1016/S0960-0760(00)00105-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:287 / 296
页数:10
相关论文
共 85 条
  • [11] Postnatal sex reversal of the ovaries in mice lacking estrogen receptors α and β
    Couse, JF
    Hewitt, SC
    Bunch, DO
    Sar, M
    Walker, VR
    Davis, BJ
    Korach, KS
    [J]. SCIENCE, 1999, 286 (5448) : 2328 - 2331
  • [12] Tissue distribution and quantitative analysis of estrogen receptor-alpha (ER alpha) and estrogen receptor-beta (ER beta) messenger ribonucleic acid in the wild-type and ER alpha-knockout mouse
    Couse, JF
    Lindzey, J
    Grandien, K
    Gustafsson, JA
    Korach, KS
    [J]. ENDOCRINOLOGY, 1997, 138 (11) : 4613 - 4621
  • [13] ANALYSIS OF TRANSCRIPTION AND ESTROGEN INSENSITIVITY IN THE FEMALE MOUSE AFTER TARGETED DISRUPTION OF THE ESTROGEN-RECEPTOR GENE
    COUSE, JF
    CURTIS, SW
    WASHBURN, TF
    LINDZEY, J
    GOLDING, TS
    LUBAHN, DB
    SMITHIES, O
    KORACH, KS
    [J]. MOLECULAR ENDOCRINOLOGY, 1995, 9 (11) : 1441 - 1454
  • [14] Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-α knockout mouse
    Couse, JF
    Bunch, DO
    Lindzey, J
    Schomberg, DW
    Korach, KS
    [J]. ENDOCRINOLOGY, 1999, 140 (12) : 5855 - 5865
  • [15] Estrogen receptor null mice: What have we learned and where will they lead us?
    Couse, JF
    Korach, KS
    [J]. ENDOCRINE REVIEWS, 1999, 20 (03) : 358 - 417
  • [16] Disruption of estrogen signaling does not prevent progesterone action in the estrogen receptor or knockout mouse uterus
    Curtis, SW
    Clark, J
    Myers, P
    Korach, KS
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (07) : 3646 - 3651
  • [17] DANIEL CW, 1987, CANCER RES, V47, P6052
  • [18] Estrogenic responses in estrogen receptor-alpha deficient mice reveal a distinct estrogen signaling pathway
    Das, SK
    Taylor, JA
    Korach, KS
    Paria, BC
    Dey, SK
    Lubahn, DB
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (24) : 12786 - 12791
  • [19] Impairing follicle-stimulating hormone (FSH) signaling in vivo:: Targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance
    Dierich, A
    Sairam, MR
    Monaco, L
    Fimia, GM
    Gansmuller, A
    LeMeur, M
    Sassone-Corsi, P
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (23) : 13612 - 13617
  • [20] Donaldson KM, 1996, J ANDROL, V17, P91