Direct synthesis of (+)-erogorgiaene through a kinetic enantiodifferentiating step

被引：67

作者：

Davies, HML ^{[1
]}

Walji, AM ^{[1
]}

机构：

[1] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 11期

关键词：

C-H activation; enantioselectivity; natural products; terpenoids; total synthesis;

D O I：

10.1002/anie.200462227

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) The combined approach of C-H activation and a Cope rearrangement catalyzed by a rhodium catalyst [Rh2(R-dosp) 4] (dosp = (N-dodecylbenzenesulfonyl)prolinate) is shown to be a very effective method for the construction of the three stereogenic centers (marked in red, see scheme) present in the diterpene erogorgiaene (1). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1733 / 1735

页数：3

共 17 条

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