Healthcare-associated rotavirus gastroenteritis in a large paediatric hospital in the UK

被引:8
作者
Cunliffe, N. A.
Allan, C.
Lowe, S. J.
Sopwith, W.
Booth, A. J.
Nakagomi, O.
Regan, M.
Hart, C. A.
机构
[1] Univ Liverpool, Dept Med Microbiol & Genitourinary Med, Liverpool L69 3GA, Merseyside, England
[2] Royal Liverpool Childrens NHS Trust, Liverpool, Merseyside, England
[3] Hlth Protect Agency NW, Liverpool, Merseyside, England
[4] Nagasaki Univ, Grad Sch Biomed Sci, Nagasaki, Japan
关键词
rotavirus; paediatric; gastroenteritis; healthcare-associated vaccine;
D O I
10.1016/j.jhin.2007.07.021
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Rotavirus is a major cause of acute, community-acquired gastroenteritis in infants and young children but its importance in healthcare-associated paediatric gastroenteritis is much less well understood. A prospective study was undertaken at the Royal Liverpool Children's NHS Trust, Liverpool, UK. We enrolled 243 children with acute gastroenteritis (AGE) who were hospitalised between January and May 2006. Rotavirus was detected in faecal. specimens by enzyme immunoassay. This virus was responsible for 17/91 cases (19%) of heatthcare-associated AGE and 54/152 cases (36%) of community-acquired AGE. Sixteen children with healthcare-associated acute rotavirus gastroenteritis required source isolation and eight received intravenous rehydration. We conclude that rotavirus is an important cause of healthcare-associated AGE in a large paediatric hospital. Rotavirus vaccines represent a public health tool. that could prevent the majority of symptomatic rotavirus infections within this healthcare setting. (c) 2007 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:240 / 244
页数:5
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