Enzymatic formation of C-terminal amides

被引：85

作者：

Kulathila, R

Merkler, KA

Merkler, DJ

机构：

[1] Novartis Pharmaceut Inc, Xray Crystallog Dept, Summit, NJ 07901 USA

[2] Duquesne Univ, Dept Chem & Biochem, Pittsburgh, PA 15282 USA

来源：

NATURAL PRODUCT REPORTS | 1999年 / 16卷 / 02期

关键词：

D O I：

10.1039/a801346b

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：145 / 154

页数：10

共 102 条

[11] Structural requirements for 5-HT2A and 5-HT1A serotonin receptor potentiation by the biologically active lipid oleamide [J].

Boger, DL ;

Patterson, JE ;

Jin, Q .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (08) :4102-4107

[12] Structural investigations on the coordination environment of the active-site copper centers of recombinant bifunctional peptidylglycine alpha-amidating enzyme [J].

Boswell, JS ;

Reedy, BJ ;

Kulathila, R ;

Merkler, D ;

Blackburn, NJ .

BIOCHEMISTRY, 1996, 35 (38) :12241-12250

[13] 4-PHENYL-3-BUTENOIC ACID, AN INVIVO INHIBITOR OF PEPTIDYLGLYCINE HYDROXYLASE (PEPTIDE AMIDATING ENZYME) [J].

BRADBURY, AF ;

MISTRY, J ;

ROOS, BA ;

SMYTH, DG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 189 (02) :363-368

[14] MECHANISM OF C-TERMINAL AMIDE FORMATION BY PITUITARY ENZYMES [J].

BRADBURY, AF ;

FINNIE, MDA ;

SMYTH, DG .

NATURE, 1982, 298 (5875) :686-688

[15]

BRADBURY AF, 1991, PEPTIDES 1990, P763

[16]

BRADBURY AF, 1991, PEPTIDE BIOSYNTHESIS, P231

[17] CORRELATION OF COPPER VALENCY WITH PRODUCT FORMATION IN SINGLE TURNOVERS OF DOPAMINE BETA-MONOOXYGENASE [J].

BRENNER, MC ;

KLINMAN, JP .

BIOCHEMISTRY, 1989, 28 (11) :4664-4670

[18] RAPID FREEZE-QUENCH AND CHEMICAL-QUENCH STUDIES OF DOPAMINE BETA-MONOOXYGENASE - COMPARISON OF PRE-STEADY-STATE AND STEADY-STATE PARAMETERS [J].

BRENNER, MC ;

MURRAY, CJ ;

KLINMAN, JP .

BIOCHEMISTRY, 1989, 28 (11) :4656-4664

[19] CHEMICAL-STABILITY AND PLASMA-CATALYZED DEALKYLATION OF PEPTIDYL-ALPHA-HYDROXYGLYCINE DERIVATIVES - INTERMEDIATES IN PEPTIDE ALPHA-AMIDATION [J].

BUNDGAARD, H ;

KAHNS, AH .

PEPTIDES, 1991, 12 (04) :745-748

[20] SELECTIVE REACTION OF GLYCINE RESIDUES IN HYDROGEN-ATOM TRANSFER FROM AMINO-ACID DERIVATIVES [J].

BURGESS, VA ;

EASTON, CJ ;

HAY, MP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (03) :1047-1052

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