Experimenting with Theoretical Motor Neuroscience

被引:15
作者
Ajemian, Robert [1 ]
Hogan, Neville [1 ,2 ,3 ]
机构
[1] MIT, McGovern Inst Brain Res, Cambridge, MA 02139 USA
[2] MIT, Dept Mech Engn, Cambridge, MA 02139 USA
[3] MIT, Dept Brain & Cognit Sci, Cambridge, MA 02139 USA
关键词
Equilibrium Point Theory; falsification; Optimal Feedback Control; theoretical motor neuroscience; EQUILIBRIUM-POINT HYPOTHESIS; TRAJECTORY FORMATION; MOVEMENT; BIOMECHANICS; IMPEDANCE; PRINCIPLE; ACCURACY; FEEDBACK; MUSCLES; POSTURE;
D O I
10.1080/00222895.2010.529332
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Motor neuroscience is well over 100 years old, with seminal work such as G. T. Fritz and E. Hitzig's discovery of motor cortex occurring in 1870. Theoretical motor neuroscience has been ongoing for at least the last 50 years. How mature a scientific discipline is motor neuroscience? Are experimentalists and theoreticians working together productively to help the field progress? This article addresses these questions by advancing the following theses. Motor neuroscience remains at a descriptive stage due to the incredible complexity of the problem to be solved. The proliferation of modelsand distinct modeling campsstems from the absence of unifying conceptual constructs. To advance the field, theoreticians must rely more heavily on the concept of falsification by producing models that lend themselves to clear experimental testing.
引用
收藏
页码:333 / 342
页数:10
相关论文
共 48 条
[41]   The uncontrolled manifold concept:: identifying control variables for a functional task [J].
Scholz, JP ;
Schöner, G .
EXPERIMENTAL BRAIN RESEARCH, 1999, 126 (03) :289-306
[42]   An undulatory theory of the mechanics of atoms and molecules [J].
Schrodinger, E .
PHYSICAL REVIEW, 1926, 28 (06) :1049-1070
[43]   Reply to 'One motor cortex, two different views' [J].
Stephen H. Scott .
Nature Neuroscience, 2000, 3 (10) :964-965
[44]   A computational neuroanatomy for motor control [J].
Shadmehr, Reza ;
Krakauer, John W. .
EXPERIMENTAL BRAIN RESEARCH, 2008, 185 (03) :359-381
[45]   Twitches versus movements: A story of motor cortex [J].
Taylor, CSR ;
Gross, CG .
NEUROSCIENTIST, 2003, 9 (05) :332-342
[46]   Optimal feedback control as a theory of motor coordination [J].
Todorov, E ;
Jordan, MI .
NATURE NEUROSCIENCE, 2002, 5 (11) :1226-1235
[47]   Limb Stiffness Is Modulated With Spatial Accuracy Requirements During Movement in the Absence of Destabilizing Forces [J].
Wong, Jeremy ;
Wilson, Elizabeth T. ;
Malfait, Nicole ;
Gribble, Paul L. .
JOURNAL OF NEUROPHYSIOLOGY, 2009, 101 (03) :1542-1549
[48]   INFORMATION, COMMUNICATION, KNOWLEDGE [J].
ZIMAN, JM .
NATURE, 1969, 224 (5217) :318-&