Regio- and stereoselective synthesis of bis-spiropyrazoline-5,3′-chroman(thiochroman)-4-one derivatives via bis-nitrilimines

被引：39

作者：

Dawood, KM ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt

来源：

TETRAHEDRON | 2005年 / 61卷 / 22期

关键词：

bis-nitrilimines; thiochromanones; chromanones; spiro-heterocycles; bipyrazoles;

D O I：

10.1016/j.tet.2005.03.083

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regioselective 1,3-dipolar cycloaddition of the bis-nitrilimines with the benzylidene derivatives of chroman-4-one and thiochroman-4-one afforded the corresponding bis-spiropyrazoline derivatives. X-ray analysis was used in the elucidation of the regio- and stereochernistry of the products. Similar reactions of the bis-nitrilimines with 2-benzylidene-3-coumaranone furnished 3,3'-bipyrazole derivatives. (c) 2005 Elsevier Ltd. All rights reserved.

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收藏

页码：5229 / 5233

页数：5

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