What is new in vitamin D: 2006-2007

被引：64

作者：

Bikle, Daniel D. ^{[1
]}

机构：

[1] Univ Calif San Francisco, San Francisco, CA 94143 USA

[2] Vet Affairs Med Ctr, San Francisco, CA USA

来源：

CURRENT OPINION IN RHEUMATOLOGY | 2007年 / 19卷 / 04期

关键词：

cancer; diabetes; innate immunity; transcription; vitamin D; D-RECEPTOR; 1,25-DIHYDROXYVITAMIN D-3; EXPRESSION; CANCER; PROTEIN; LIGAND; CELLS; BONE; GENE; 1-ALPHA-HYDROXYLASE;

D O I：

10.1097/BOR.0b013e32818e9d58

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The wide distribution of the vitamin D receptor provides a number of clinical targets for vitamin D and its analogs. The wide distribution of CYP27B1, the enzyme required to convert circulating 25OHD to 1,25(OH)(2)D enables a number of cells to make their own 1,25(OH)(2)D-3 if circulating 25OHD levels are maintained. These newer studies emphasize that vitamin D is not just for bones, and maintaining adequate levels is important for many tissues.

引用

页码：383 / 388

页数：6

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