Study of the mechanism of electron-transfer quenching by boron-nitrogen adducts in fluorescent sensors

被引：115

作者：

Franzen, S ^{[1
]}

Ni, WJ ^{[1
]}

Wang, BH ^{[1
]}

机构：

[1] N Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 2003年 / 107卷 / 47期

关键词：

D O I：

10.1021/jp027457a

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The mechanism of the change in fluorescence quenching by the amine in boronic acid-based carbohydrate sensor molecules has been explored using density functional theory (DFT). The geometric constraints of the system have been studied in both intra- and intermolecular model systems of the boron-nitrogen (B-N) bonding interaction. The effect of the B-N bonding on the rate of electron-transfer (ET) quenching of the anthracene acceptor by an amine donor is considered using a theoretical model. The results suggest a new mechanism other than B-N bond strength change for fluorescent switching in biosensors that involve interaction of boron and nitrogen affected by boronate ester formation.

引用

页码：12942 / 12948

页数：7

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