Potassium channels: from scorpion venoms to high-resolution structure

被引：101

作者：

Garcia, ML

Gao, YD

McManus, OB

Kaczorowski, GJ

机构：

[1] Merck Res Labs, Dept Membrane Biochem & Biophys, Rahway, NJ 07065 USA

[2] Merck Res Labs, Dept Mol Syst, Rahway, NJ 07065 USA

来源：

TOXICON | 2001年 / 39卷 / 06期

关键词：

D O I：

10.1016/S0041-0101(00)00214-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：739 / 748

页数：10

共 46 条

[1] TOPOLOGY OF THE PORE-REGION OF A K+ CHANNEL REVEALED BY THE NMR-DERIVED STRUCTURES OF SCORPION TOXINS [J].

AIYAR, J ;

WITHKA, JM ;

RIZZI, JP ;

SINGLETON, DH ;

ANDREWS, GC ;

LIN, W ;

BOYD, J ;

HANSON, DC ;

SIMON, M ;

DETHLEFS, B ;

LEE, CL ;

HALL, JE ;

GUTMAN, GA ;

CHANDY, KG .

NEURON, 1995, 15 (05) :1169-1181

[2] ANALYSIS OF SIDE-CHAIN ORGANIZATION ON A REFINED MODEL OF CHARYBDOTOXIN - STRUCTURAL AND FUNCTIONAL IMPLICATIONS [J].

BONTEMS, F ;

GILQUIN, B ;

ROUMESTAND, C ;

MENEZ, A ;

TOMA, F .

BIOCHEMISTRY, 1992, 31 (34) :7756-7764

[3] REFINED STRUCTURE OF CHARYBDOTOXIN - COMMON MOTIFS IN SCORPION TOXINS AND INSECT DEFENSINS [J].

BONTEMS, F ;

ROUMESTAND, C ;

GILQUIN, B ;

MENEZ, A ;

TOMA, F .

SCIENCE, 1991, 254 (5037) :1521-1523

[4] pH-dependent gating in the Streptomyces lividans K+ channel [J].

Cuello, LG ;

Romero, JG ;

Cortes, DM ;

Perozo, E .

BIOCHEMISTRY, 1998, 37 (10) :3229-3236

[5] Determination of the three-dimensional solution structure of noxiustoxin: Analysis of structural differences with related short-chain scorpion toxins [J].

Dauplais, M ;

Gilquin, B ;

Possani, LD ;

GurrolaBriones, G ;

Roumestand, C ;

Menez, A .

BIOCHEMISTRY, 1995, 34 (51) :16563-16573

[6] The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity [J].

Doyle, DA ;

Cabral, JM ;

Pfuetzner, RA ;

Kuo, AL ;

Gulbis, JM ;

Cohen, SL ;

Chait, BT ;

MacKinnon, R .

SCIENCE, 1998, 280 (5360) :69-77

[7] KALIOTOXIN(1-37) SHOWS STRUCTURAL DIFFERENCES WITH RELATED POTASSIUM CHANNEL BLOCKERS [J].

FERNANDEZ, I ;

ROMI, R ;

SZENDEFFY, S ;

MARTINEAUCLAIRE, MF ;

ROCHAT, H ;

VANRIETSCHOTEN, J ;

PONS, M ;

GIRALT, E .

BIOCHEMISTRY, 1994, 33 (47) :14256-14263

[8]

GALVEZ A, 1990, J BIOL CHEM, V265, P11083

[9]

Garcia M L, 1997, Adv Pharmacol, V39, P425, DOI 10.1016/S1054-3589(08)60078-2

[10] CHARYBDOTOXIN AND ITS EFFECTS ON POTASSIUM CHANNELS [J].

GARCIA, ML ;

KNAUS, HG ;

MUNUJOS, P ;

SLAUGHTER, RS ;

KACZOROWSKI, GJ .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1995, 269 (01) :C1-C10

← 1 2 3 4 5 →