Antioxidant flavonoid glycosides from the leaves of Ficus pumila L.

被引:119
作者
Abraham, Leong Cheng Ning [1 ,2 ]
Masakuni, Tako [1 ]
Isao, Hanashiro [3 ]
Hajime, Tamaki [1 ]
机构
[1] Univ Ryukyus, Fac Agr, Dept Biosci & Biotechnol, Okinawa 9030213, Japan
[2] Kagoshima Univ, United Grad Sch Agr Sci, Dept Biochem & Appl Biosci, Okinawa 9030213, Japan
[3] Kagoshima Univ, Fac Agr, Dept Biochem Sci & Technol, Kagoshima 8900065, Japan
关键词
Ficus pumila L; flavonoid glycosides; antioxidant;
D O I
10.1016/j.foodchem.2007.12.069
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The Okinawan folks in Japan use Ficus pumila L. as a beverage or herbal medicine to treat diabetes and high blood pressure. Four flavonoid glycosides were isolated and identified as rutin (1 and 3), apigenin 6-neohesperidose (2), kaempferol 3-robinobioside (4) and kaempferol 3-rutinoside (5). Among these compounds, rutin exhibited the strongest antioxidant activity in DPPH radical scavenging assay and superoxide radical inhibition assay. The preparation of Ooitabi leaves in water provide sufficient amount of flavonoid glycosides to the Okinawan although 50% of aqueous ethanol extracted these flavonoid glycosides more effectively. These results show the potential of Ooitabi leaves as a natural source of antioxidant for health management. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:415 / 420
页数:6
相关论文
共 20 条
[1]  
Agrawal P.K., 1989, CARBON 13 NMR FLAVON, P283
[2]  
ANIYA Y, 2002, OK INT C LONG P NAH, P50
[3]   ROLE OF OXIDATIVE STRESS IN DEVELOPMENT OF COMPLICATIONS IN DIABETES [J].
BAYNES, JW .
DIABETES, 1991, 40 (04) :405-412
[4]  
BENZIE IFF, 2002, OK INT C LONG P NAH, P38
[5]   FLAVONOL GLYCOSIDES FROM LEAVES OF STRYCHNOS-VARIABILIS [J].
BRASSEUR, T ;
ANGENOT, L .
PHYTOCHEMISTRY, 1986, 25 (02) :563-564
[6]   Inhibition of advanced glycation end product formation on collagen by rutin and its metabolites [J].
Cervantes-Laurean, Daniel ;
Schramm, Derek D. ;
Jacobson, Elaine L. ;
Halaweish, Ihab ;
Bruckner, Geza G. ;
Boissonneault, Gilbert A. .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2006, 17 (08) :531-540
[7]  
IMANARI T, 1977, IGAKU NO AYUMI, V101, P496
[8]   Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions [J].
La Casa, C ;
Villegas, I ;
de la Lastra, CA ;
Motilva, V ;
Calero, MJM .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 71 (1-2) :45-53
[9]   Structural requirements of flavonoids for inhibition of protein glycation and radical scavenging activities [J].
Matsuda, H ;
Wang, T ;
Managi, H ;
Yoshikawa, M .
BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 11 (24) :5317-5323
[10]  
Mitsuhashi H., 1988, ILLUSTRATED MED PLAN