Synthesis of calix[4]arene library substituted with peptides at the upper rim

被引：15

作者：

Hioki, H ^{[1
]}

Ohnishi, Y ^{[1
]}

Kubo, M ^{[1
]}

Nashimoto, E ^{[1
]}

Kinoshita, Y ^{[1
]}

Samejima, M ^{[1
]}

Kodama, M ^{[1
]}

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Yamashiro, Tokushima 7708514, Japan

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 03期

关键词：

calixarenes; combinatorial library; binding assay; chemosensors;

D O I：

10.1016/j.tetlet.2003.10.215

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A fluorescence-labeled calix[4]arene library substituted with peptides at the upper rim was synthesized. Screening of the library for binding a dye-labeled oligopeptide indicated that some peptidocalix[4]arenes selectively bind the oligopeptide. The chemosensitivity of the library members for a target peptide was also investigated. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：561 / 564

页数：4

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