The alternative genome

被引：31

作者：

Ast, G ^{[1
]}

机构：

[1] Tel Aviv Univ, Dept Human Genet & Mol Med, IL-69978 Tel Aviv, Israel

来源：

SCIENTIFIC AMERICAN | 2005年 / 292卷 / 04期

关键词：

D O I：

10.1038/scientificamerican0405-58

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Following the publishing of the human genome map, geneticists were unable to believe that humans had approximately only 30,000 genes despite the production of 90,000 different proteins. A process known as alternative splicing is responsible for this process as a small number of genes are capable of generating amuch larger assortment of proteins.

引用

页码：58 / 65

页数：8

共 4 条

[1] How did alternative splicing evolve? [J].

Ast, G .

NATURE REVIEWS GENETICS, 2004, 5 (10) :773-782

[2] Alternative splicing: increasing diversity in the proteomic world [J].

Graveley, BR .

TRENDS IN GENETICS, 2001, 17 (02) :100-107

[3] The hidden genetic program of complex organisms [J].

Mattick, JS .

SCIENTIFIC AMERICAN, 2004, 291 (04) :60-67

[4] Splicing regulation as a potential genetic modifier [J].

Nissim-Rafinia, M ;

Kerem, B .

TRENDS IN GENETICS, 2002, 18 (03) :123-127

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