Transmission of 2009 Pandemic Influenza A (H1N1) Virus among Healthcare Personnel-Southern California, 2009

被引:34
作者
Jaeger, Jenifer L. [1 ]
Patel, Minal [1 ,2 ]
Dharan, Nila [1 ,3 ]
Hancock, Kathy [3 ]
Meites, Elissa [1 ,2 ]
Mattson, Christine [1 ,4 ]
Gladden, Matt [1 ,5 ]
Sugerman, David [1 ,3 ]
Doshi, Saumil [1 ,3 ]
Blau, Dianna [1 ,2 ]
Harriman, Kathleen [6 ]
Whaley, Melissa [3 ]
Sun, Hong [3 ]
Ginsberg, Michele [7 ]
Kao, Annie S. [7 ]
Kriner, Paula [8 ]
Lindstrom, Stephen [3 ]
Jain, Seema [3 ]
Katz, Jacqueline [3 ]
Finelli, Lyn [3 ]
Olsen, Sonja J. [3 ]
Kallen, Alexander J. [2 ]
机构
[1] Ctr Dis Control & Prevent CDC, Epidem Intelligence Serv, Atlanta, GA USA
[2] CDC, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USA
[3] CDC, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA
[4] CDC, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA 30333 USA
[5] CDC, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USA
[6] Calif Dept Publ Hlth, Sacramento, CA USA
[7] San Diego Cty Hlth & Human Serv Agcy, San Diego, CA USA
[8] Imperial Cty Publ Hlth Dept, El Centro, CA USA
关键词
INFECTION-CONTROL MEASURES; HAND HYGIENE; WORKERS; ILLNESS; MASK; SARS; US;
D O I
10.1086/662709
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
OBJECTIVE. In April 2009, 2009 pandemic influenza A (H1N1) (hereafter, pH1N1) virus was identified in California, which caused widespread illness throughout the United States. We evaluated pH1N1 transmission among exposed healthcare personnel (HCP) and assessed the use and effectiveness of personal protective equipment (PPE) early in the outbreak. DESIGN. Cohort study. SETTING. Two hospitals and 1 outpatient clinic in Southern California during March 28-April 24, 2009. PARTICIPANTS. Sixty-three HCP exposed to 6 of the first 8 cases of laboratory-confirmed pH1N1 in the United States. METHODS. Baseline and follow-up questionnaires were used to collect demographic, epidemiologic, and clinical data. Paired serum samples were obtained to test for pH1N1-specific antibodies by microneutralization and hemagglutination-inhibition assays. Serology results were compared with HCP work setting, role, and self-reported PPE use. RESULTS. Possible healthcare-associated pH1N1 transmission was identified in 9 (14%) of 63 exposed HCP; 6 (67%) of 9 seropositive HCP had asymptomatic infection. The highest attack rates occurred among outpatient HCP (6/19 [32%]) and among allied health staff (eg, technicians; 8/33 [24%]). Use of mask or N95 respirator was associated with remaining seronegative (P = 047). Adherence to PPE recommendations for preventing transmission of influenza virus and other respiratory pathogens was inadequate, particularly in outpatient settings. CONCLUSIONS. pH1N1 transmission likely occurred in healthcare settings early in the pandemic associated with inadequate PPE use. Organizational support for a comprehensive approach to infectious hazards, including infection prevention training for inpatient-and outpatient-based HCP, is essential to improve HCP and patient safety. Infect Control Hosp Epidemiol 2011; 32(12): 1149-1157
引用
收藏
页码:1149 / 1157
页数:9
相关论文
共 46 条
  • [31] Paediatric emergency department staff perceptions of infection control measures against severe acute respiratory syndrome
    Parker, MJ
    Goldman, RD
    [J]. EMERGENCY MEDICINE JOURNAL, 2006, 23 (05) : 349 - 353
  • [32] Does Influenza Transmission Occur from Asymptomatic Infection or Prior to Symptom Onset?
    Patrozou, Eleni
    Mermel, Leonard A.
    [J]. PUBLIC HEALTH REPORTS, 2009, 124 (02) : 193 - 196
  • [33] Respiratory hygiene in the emergency department
    Rothman, Richard E.
    Irvin, Charlene B.
    Moran, Gregory J.
    Sauer, Lauren
    Bradshaw, Ylisabyth S.
    Fry, Robert B., Jr.
    Josephine, Elaine B.
    Ledyard, Holly K.
    Hirshon, Jon Mark
    [J]. ANNALS OF EMERGENCY MEDICINE, 2006, 48 (05) : 570 - 582
  • [34] Influenza in the acute hospital setting
    Salgado, CD
    Farr, BM
    Hall, KK
    Hayden, FG
    [J]. LANCET INFECTIOUS DISEASES, 2002, 2 (03) : 145 - 155
  • [35] Which Health Care Workers Were Most Affected During the Spring 2009 H1N1 Pandemic?
    Santos, Cynthia D.
    Bristow, Robert B.
    Vorenkamp, Jaclyn V.
    [J]. DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS, 2010, 4 (01) : 47 - 54
  • [36] Siegel JD., 2019, 2007 guideline for isolation precautions: Preventing transmission of infectious agents in healthcare settings
  • [37] Virulent epidemics and scope of Healthcare workers' duty of care
    Sokol, Daniel K.
    [J]. EMERGING INFECTIOUS DISEASES, 2006, 12 (08) : 1238 - 1241
  • [38] Peripatetic health-care workers as potential superspreaders
    Temime, Laura
    Opatowski, Lulla
    Pannet, Yohan
    Brun-Buisson, Christian
    Boelle, Pierre Yves
    Guillemot, Didier
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (43) : 18420 - 18425
  • [39] Survival of two avian respiratory viruses on porous and nonporous surfaces
    Tiwari, A
    Patnayak, DP
    Chander, Y
    Parsad, M
    Goyal, SM
    [J]. AVIAN DISEASES, 2006, 50 (02) : 284 - 287
  • [40] Viral Load in Patients Infected With Pandemic H1N1 2009 Influenza A Virus
    To, Kelvin K. W.
    Chan, Kwok-Hung
    Li, Iris W. S.
    Tsang, Tak-Yin
    Tse, Herman
    Chan, Jasper F. W.
    Hung, Ivan F. N.
    Lai, Sik-To
    Leung, Chi-Wai
    Kwan, Yat-Wah
    Lau, Yu-Lung
    Ng, Tak-Keung
    Cheng, Vincent C. C.
    Peiris, Joseph S. M.
    Yuen, Kwok-Yung
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2010, 82 (01) : 1 - 7