New steroidal alkaloids from Sarcococca saligna

被引：19

作者：

Atta-Ur-Rahman ^{[1
]}

Feroz, F ^{[1
]}

ul-Haq, Z ^{[1
]}

Nawaz, SA ^{[1
]}

Khan, MR ^{[1
]}

Choudhary, MI ^{[1
]}

机构：

[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan

来源：

NATURAL PRODUCT RESEARCH | 2003年 / 17卷 / 04期

关键词：

Anti-cholinesterase; Buxaceae; Salonine-A; Salonine-B; Sarcococca saligna; Steroidal alkaloids;

D O I：

10.1080/1057563021000051086

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new steroidal alkaloids, salonine-A [(20S)-20-(N,N-dimethylamino)-3beta-(tigloylamino)-5alpha-pregn-14-en-2beta, 4beta-diol] (1), and salonine-B [(20S)-20-(N,N-dimethylamino)-3beta- methoxy-pregn-5,16-diene] (2), were isolated from the MeOH extract of Sarcococca saligna, along with a known base, alkaloid-C (3). Their structures were elucidated on the basis of spectroscopic methods. All three compounds were found to be cholinesterase inhibitors.

引用

页码：235 / 241

页数：7

共 19 条

[1]

Atta-ur-Rahman, 2002, HELV CHIM ACTA, V85, P678, DOI 10.1002/1522-2675(200202)85:2&lt

[2]

678::AID-HLCA678&gt

[3]

3.0.CO

[4]

2-2

[5]

Atta-ur-Rahman, 1998, NAT PROD LETT, V12, P161, DOI 10.1080/10575639808048277

[6] Antibacterial steroidal alkaloids from Sarcococca saligna [J].

Atta-ur-Rahman ;

Anjum, S ;

Farooq, A ;

Khan, MR ;

Parveen, Z ;

Choudhary, MI .

JOURNAL OF NATURAL PRODUCTS, 1998, 61 (02) :202-206

[7]

Atta-Ur-Rahman, 1998, NAT PROD LETT, V11, P81

[8] Phytochemical studies on steroidal alkaloids of Sarcococca saligna [J].

Atta-ur-Rahman ;

Anjum, S ;

Farooq, A ;

Khan, MR ;

Choudhary, MI .

NATURAL PRODUCT LETTERS, 1998, 11 (04) :297-304

[9] Steroidal alkaloids from Sarcococca saligna [J].

AttaurRahman ;

Khan, MR ;

Choudhary, MI ;

Iqbal, MZ .

PHYTOCHEMISTRY, 1997, 45 (04) :861-864

[10] 4 NEW STEROIDAL ALKALOIDS FROM PACHYSANDRA-AXILLARIS [J].

CHIU, MH ;

NIE, RL ;

LI, ZR ;

ZHOU, J .

JOURNAL OF NATURAL PRODUCTS, 1992, 55 (01) :25-28

← 1 2 →