NMR spectroscopy as a tool for structure-based drug design

[1] SOLUTION STRUCTURE OF KISTRIN, A POTENT PLATELET-AGGREGATION INHIBITOR AND GP-IIB-IIIA ANTAGONIST [J]. SCIENCE, 1991, 253 (5018) : 445 - 448

[2] SYNTHESIS, CONFORMATION, AND IMMUNOSUPPRESSIVE ACTIVITY OF A CONFORMATIONALLY RESTRICTED CYCLOSPORINE LACTAM ANALOG [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (09) : 1805 - 1815

[3] SYNTHESIS, CONFORMATION, AND IMMUNOSUPPRESSIVE ACTIVITIES OF 3 ANALOGS OF CYCLOSPORINE-A MODIFIED IN THE 1-POSITION [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (03) : 999 - 1009

[4] EFFECTS OF ION-BINDING ON THE BACKBONE DYNAMICS OF CALBINDIN-D9K DETERMINED BY N-15 NMR RELAXATION [J]. BIOCHEMISTRY, 1993, 32 (37) : 9832 - 9844

[5] STRUCTURE-BASED DESIGN OF A CYCLOPHILIN-CALCINEURIN BRIDGING LIGAND [J]. SCIENCE, 1993, 262 (5131) : 248 - 250

[6] fd coat protein structure in membrane environments: Structural dynamics of the loop between the hydrophobic trans-membrane helix and the amphipathic in-plane helix [J]. JOURNAL OF MOLECULAR BIOLOGY, 1997, 270 (03) : 481 - 495

[7] ANALYTICAL TECHNIQUES IN COMBINATORIAL CHEMISTRY - MAS CH CORRELATION IN SOLVENT-SWOLLEN RESIN [J]. JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (09) : 2650 - 2651

[8] STRUCTURE DETERMINATION IN COMBINATORIAL CHEMISTRY - UTILIZATION OF MAGIC-ANGLE-SPINNING HMQC AND TOCSY NMR-SPECTRA IN THE STRUCTURE DETERMINATION OF WANG-BOUND LYSINE [J]. TETRAHEDRON LETTERS, 1995, 36 (30) : 5311 - 5314

[9] DESIGN OF ENZYME-INHIBITORS USING ITERATIVE PROTEIN CRYSTALLOGRAPHIC ANALYSIS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (07) : 1925 - 1934

[10] Archer SJ, 1996, ANNU REP MED CHEM, V31, P299

[1] SOLUTION STRUCTURE OF KISTRIN, A POTENT PLATELET-AGGREGATION INHIBITOR AND GP-IIB-IIIA ANTAGONIST [J]. SCIENCE, 1991, 253 (5018) : 445 - 448

[2] SYNTHESIS, CONFORMATION, AND IMMUNOSUPPRESSIVE ACTIVITY OF A CONFORMATIONALLY RESTRICTED CYCLOSPORINE LACTAM ANALOG [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (09) : 1805 - 1815

[3] SYNTHESIS, CONFORMATION, AND IMMUNOSUPPRESSIVE ACTIVITIES OF 3 ANALOGS OF CYCLOSPORINE-A MODIFIED IN THE 1-POSITION [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (03) : 999 - 1009

[4] EFFECTS OF ION-BINDING ON THE BACKBONE DYNAMICS OF CALBINDIN-D9K DETERMINED BY N-15 NMR RELAXATION [J]. BIOCHEMISTRY, 1993, 32 (37) : 9832 - 9844

[5] STRUCTURE-BASED DESIGN OF A CYCLOPHILIN-CALCINEURIN BRIDGING LIGAND [J]. SCIENCE, 1993, 262 (5131) : 248 - 250

[6] fd coat protein structure in membrane environments: Structural dynamics of the loop between the hydrophobic trans-membrane helix and the amphipathic in-plane helix [J]. JOURNAL OF MOLECULAR BIOLOGY, 1997, 270 (03) : 481 - 495

[7] ANALYTICAL TECHNIQUES IN COMBINATORIAL CHEMISTRY - MAS CH CORRELATION IN SOLVENT-SWOLLEN RESIN [J]. JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (09) : 2650 - 2651

[8] STRUCTURE DETERMINATION IN COMBINATORIAL CHEMISTRY - UTILIZATION OF MAGIC-ANGLE-SPINNING HMQC AND TOCSY NMR-SPECTRA IN THE STRUCTURE DETERMINATION OF WANG-BOUND LYSINE [J]. TETRAHEDRON LETTERS, 1995, 36 (30) : 5311 - 5314

[9] DESIGN OF ENZYME-INHIBITORS USING ITERATIVE PROTEIN CRYSTALLOGRAPHIC ANALYSIS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (07) : 1925 - 1934

[10] Archer SJ, 1996, ANNU REP MED CHEM, V31, P299