The CoFactor database: organic cofactors in enzyme catalysis

被引：54

作者：

Fischer, Julia D. ^{[1
]}

Holliday, Gemma L. ^{[1
]}

Thornton, Janet M. ^{[1
]}

机构：

[1] EMBL EBI, Cambridge CB10 1SD, England

来源：

BIOINFORMATICS | 2010年 / 26卷 / 19期

关键词：

CLASSIFICATION; MACIE;

D O I：

10.1093/bioinformatics/btq442

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Motivation: Organic enzyme cofactors are involved in many enzyme reactions. Therefore, the analysis of cofactors is crucial to gain a better understanding of enzyme catalysis. To aid this, we have created the CoFactor database. Results: CoFactor provides a web interface to access hand-curated data extracted from the literature on organic enzyme cofactors in biocatalysis, as well as automatically collected information. CoFactor includes information on the conformational and solvent accessibility variation of the enzyme-bound cofactors, as well as mechanistic and structural information about the hosting enzymes.

引用

页码：2496 / 2497

页数：2

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