The hydrophobic effect as a mechanistic tool

被引：43

作者：

Breslow, R ^{[1
]}

Groves, K ^{[1
]}

Mayer, MU ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem, New York, NY 10027 USA

来源：

PURE AND APPLIED CHEMISTRY | 1998年 / 70卷 / 10期

关键词：

D O I：

10.1351/pac199870101933

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions in water of species with hydrophobic surfaces are slowed by the addition of antihydrophobic cosolvents if the transition states involve shielding of part of those surfaces from solvent, or speeded if the transition states are more hydrophobic than are the reactants. Using this and other tools, some displacements have been shown to occur by single elctron transfer (SET) mechanisms, others by direct nucleophilic attack with various geometries. The results correlate well with the predictions of quantum mechanical calculations.

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页码：1933 / 1938

页数：6

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