Albumin-conjugated corrole metal complexes: Extremely simple yet very efficient biomimetic oxidation systems

被引：249

作者：

Mahammed, A

Gross, Z ^{[1
]}

机构：

[1] Technion Israel Inst Technol, Dept Chem, IL-32000 Haifa, Israel

[2] Technion Israel Inst Technol, Inst Catalysis Sci & Technol, IL-32000 Haifa, Israel

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 09期

关键词：

D O I：

10.1021/ja045372c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An extremely simple biomimetic oxidation system, consisting of mixing metal complexes of amphiphilic corroles with serum albumins, utilizes hydrogen peroxide for asymmetric sulfoxidation in up to 74% ee. The album in-conjugated manganese corroles also display catalase-like activity, and mechanistic evidence points toward oxidant-coordinated manganese(III) as the prime reaction intermediate.

引用

页码：2883 / 2887

页数：5

共 43 条

[41] Catalytic sulfoxidation and epoxidation with a Mn(III) triazacorrole: Evidence for a "third oxidant" in high-valent porphyrinoid oxidations [J].