The use of non-uniform deuterium labelling ['NMR-window'] to study the NMR structure of a 21mer RNA hairpin

被引：35

作者：

Foldesi, A ^{[1
]}

Yamakage, SI ^{[1
]}

Nilsson, FPR ^{[1
]}

Maltseva, TV ^{[1
]}

Chattopadhyaya, J ^{[1
]}

机构：

[1] UNIV UPPSALA,CTR BIOMED,DEPT BIOORGAN CHEM,S-75123 UPPSALA,SWEDEN

来源：

NUCLEIC ACIDS RESEARCH | 1996年 / 24卷 / 07期

基金：

瑞典研究理事会;

关键词：

D O I：

10.1093/nar/24.7.1187

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The first synthesis of a non-uniformly deuterium labelled 21 mer RNA is reported using our 'NMR-window' concept, showing its unique application in the unambiguous NMR assignment of the nonexchangeable aromatic and sugar protons.

引用

页码：1187 / 1194

页数：8

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