26th Hohenheim Consensus Conference, September 11, 2010 Scientific substantiation of health claims: Evidence-based nutrition

被引:59
作者
Biesalski, Hans Konrad [1 ]
Aggett, Peter J. [2 ]
Anton, Robert [3 ]
Bernstein, Paul S. [4 ]
Blumberg, Jeffrey [5 ]
Heaney, Robert P. [6 ]
Henry, Jeya [7 ]
Nolan, John M. [8 ,9 ]
Richardson, David P. [10 ]
van Ommen, Ben [11 ]
Witkamp, Renger F. [12 ]
Rijkers, Ger T. [13 ,14 ]
Zoellner, Iris [15 ]
机构
[1] Univ Hohenheim, Inst Biol Chem & Nutr, D-7000 Stuttgart, Germany
[2] Univ Lancaster, Parbold, England
[3] Univ Strasbourg, Strasbourg, France
[4] Univ Utah, Sch Med, Moran Eye Ctr, Dept Ophthalmol & Visual Sci, Salt Lake City, UT USA
[5] Tufts Univ, Friedman Sch Nutr Sci & Policy, Jean Mayer USDA Human Nutr Res Ctr Aging, Antioxidants Res Lab, Boston, MA 02111 USA
[6] Creighton Univ, Omaha, NE 68178 USA
[7] Oxford Brookes Univ, Funct Food Ctr, Oxford OX3 0BP, England
[8] Waterford Inst Technol, Dept Chem & Life Sci, MPRG, Waterford, Ireland
[9] Whitfield Clin, Inst Vis Res, Waterford, Ireland
[10] DPR Nutr Ltd, Surrey, England
[11] TNO, NL-3700 AJ Zeist, Netherlands
[12] Wageningen Univ, Div Human Nutr, Dept Pharmacol & Nutr, Wageningen, Netherlands
[13] Univ Med Ctr, Dept Surg, Utrecht, Netherlands
[14] St Antonius Hosp, Lab Med Microbiol & Immunol, Nieuwegein, Netherlands
[15] Baden Wuerttemberg State Hlth Off, Stuttgart, Germany
关键词
Nutrition; Clinical trials; Health claim; Micronutrients; Regulation; GLYCEMIC INDEX; BETA-CAROTENE; MACULAR DEGENERATION; LUNG-CANCER; RISK-FACTOR; VITAMIN-E; BIOMARKERS; GLUCOSE; FOLATE; ASSOCIATION;
D O I
10.1016/j.nut.2011.04.002
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 [营养与食品卫生学];
摘要
Objective: The objective was to define the term evidence based nutrition on the basis of expert discussions and scientific evidence. Methods and procedures: The method used is the established Hohenheim Consensus Conference. The term "Hohenheim Consensus Conference" defines conferences dealing with nutrition-related topics. The major aim of the conference is to review the state of the art of a given topic with experts from different areas (basic science, clinicians, epidemiologists, etc.). Based on eight to 12 questions, the experts discuss short answers and try to come to a consensus. A scientifically based text is formulated that justifies the consensus answer. To discuss the requirements for the scientific substantiation of claims, the 26th Hohenheim Consensus Conference gathered the views of many academic experts in the field of nutritional research and asked these experts to address the various aspects of a claims substantiation process and the possibilities and limitations of the different approaches. Results: The experts spent a day presenting and discussing their views and arrived at several consensus statements that can serve as guidance for bodies performing claims assessments in the framework of regulatory systems. Conclusion: The 26th Hohenheim Consensus Conference addresses some general aspects and describes the current scientific status from the point of view of six case studies to illustrate specific areas of scientific interest: carotenoids and vitamin A in relation to age-related macular degeneration, the quality of carbohydrates (as expressed by the glycemic index) in relation to health and well-being, probiotics in relation to intestinal and immune functions, micronutrient intake and maintenance of normal body functions, and food components with antioxidative properties and health benefits. (C) 2011 Published by Elsevier Inc.
引用
收藏
页码:S1 / S20
页数:20
相关论文
共 79 条
[1]
Academy of Medical Sciences, 2007, ID ENV CAUS DIS SHOU, P144
[2]
AFSSA, 2003, FRAM EV SAF EFF CLAI
[3]
Passclaim*Consensus on Criteria [J].
Peter J. Aggett ;
Jean-Michel Antoine ;
Nils-Georg Asp ;
France Bellisle ;
Laura Contor ;
John H. Cummings ;
John Howlett ;
Detlef J. G. Müller ;
Christoph Persin ;
Loek T. J. Pijls ;
Gerhard Rechkemmer ;
Sandra Tuijtelaars ;
Hans Verhagen .
European Journal of Nutrition, 2005, 44 (Suppl 1) :i5-i30
[4]
alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: Effects of base-line characteristics and study compliance [J].
Albanes, D ;
Heinonen, OP ;
Taylor, PR ;
Virtamo, J ;
Edwards, BK ;
Rautalahti, M ;
Hartman, AM ;
Palmgren, J ;
Freedman, LS ;
Haapakoski, J ;
Barrett, MJ ;
Pietinen, P ;
Malila, N ;
Tala, E ;
Liippo, K ;
Salomaa, ER ;
Tangrea, JA ;
Teppo, L ;
Askin, FB ;
Taskinen, E ;
Erozan, Y ;
Greenwald, P ;
Huttunen, JK .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1996, 88 (21) :1560-1570
[5]
Markers to measure immunomodulation in human nutrition intervention studies [J].
Albers, R ;
Antoine, JM ;
Bourdet-Sicard, R ;
Calder, PC ;
Gleeson, M ;
Lesourd, B ;
Samartín, S ;
Sanderson, IR ;
Van Loo, J ;
Vas Dias, FW ;
Watzl, B .
BRITISH JOURNAL OF NUTRITION, 2005, 94 (03) :452-481
[6]
Effects of cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid (CLA) isomers on immune function in healthy men [J].
Albers, R ;
van der Wielen, RPJ ;
Brink, EJ ;
Hendriks, HFJ ;
Dorovska-Taran, VN ;
Mohede, ICM .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2003, 57 (04) :595-603
[7]
[Anonymous], 2009, LANCET, V373, P781, DOI 10.1016/S0140-6736(09)60456-6
[8]
[Anonymous], 2009, EPIDEMIOLOGIC PERSPE, DOI [10.1186/1742-5573-6-2, DOI 10.1186/1742-5573-6-2]
[9]
[Anonymous], DIET REF INT CALC VI
[10]
[Anonymous], 1999, WHO MONOGRAPHS SELEC