Exposure to road traffic and railway noise and associations with blood pressure and self-reported hypertension: a cohort study

被引:100
作者
Sorensen, Mette [1 ]
Hvidberg, Martin [2 ]
Hoffmann, Barbara [3 ,4 ]
Andersen, Zorana J. [1 ]
Nordsborg, Rikke B. [1 ]
Lillelund, Kenneth G. [5 ]
Jakobsen, Jorgen [6 ]
Tjonneland, Anne [1 ]
Overvad, Kim [7 ,8 ]
Raaschou-Nielsen, Ole [1 ]
机构
[1] Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark
[2] Aarhus Univ, Natl Environm Res Inst, Roskilde, Denmark
[3] Univ Dusseldorf, IUF Leibniz Res Inst Environm Med, Dusseldorf, Germany
[4] Univ Dusseldorf, Fac Med, Dusseldorf, Germany
[5] Ramboll Danmark AS, Aarhus, Denmark
[6] Danish Environm Protect Agcy, Copenhagen, Denmark
[7] Aarhus Univ, Sch Publ Hlth, Dept Epidemiol, Aarhus, Denmark
[8] Aarhus Univ Hosp, Aalborg Hosp, Cardiovasc Res Ctr, Dept Cardiol, Aalborg, Denmark
关键词
blood pressure; transport noise; road traffic; railway; epidemiology; cohort; LONG-TERM EXPOSURE; AIR-POLLUTION; CARDIOVASCULAR RISK; PARTICULATE MATTER; 1ST PHASE; SLEEP; STREET; HEALTH; ADULTS; MODEL;
D O I
10.1186/1476-069X-10-92
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Background: Epidemiological studies suggest that long-term exposure to transport noise increases the risk for cardiovascular disorders. The effect of transport noise on blood pressure and hypertension is uncertain. Methods: In 1993-1997, 57,053 participants aged 50-64 year were enrolled in a population-based cohort study. At enrolment, systolic and diastolic blood pressure was measured. Incident hypertension during a mean follow-up of 5.3 years was assessed by questionnaire. Residential long-term road traffic noise (L-den) was estimated for 1- and 5-year periods preceding enrolment and preceding diagnosis of hypertension. Residential exposure to railway noise was estimated at enrolment. We conducted a cross-sectional analysis of associations between road traffic and railway noise and blood pressure at enrolment with linear regression, adjusting for long-term air pollution, meteorology and potential lifestyle confounders (N = 44,083). Incident self-reported hypertension was analyzed with Cox regression, adjusting for long-term air pollution and potential lifestyle confounders. Results: We found a 0.26 mm Hg higher systolic blood pressure (95% confidence intervals (CI): -0.11; 0.63) per 10 dB(A) increase in 1-year mean road traffic noise levels, with stronger associations in men (0.59 mm Hg (CI: 0.13; 1.05) per 10 dB(A)) and older participants (0.65 mm Hg (0.08; 1.22) per 10 dB(A)). Road traffic noise was not associated with diastolic blood pressure or hypertension. Exposure to railway noise above 60 dB was associated with 8% higher risk for hypertension (95% CI: -2%; 19%, P = 0.11). Conclusions: While exposure to road traffic noise was associated with systolic blood pressure in subgroups, we were not able to identify associations with hypertension.
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页数:11
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