Asymmetric reduction of 2-Oxo-4-phenylbutanoic acid ethyl ester by Daucus carota cell cultures

被引：46

作者：

Chadha, A ^{[1
]}

Manohar, M ^{[1
]}

Soundararajan, T ^{[1
]}

Lokeswari, TS ^{[1
]}

机构：

[1] SPIC SCI FDN, DIV BIOTECHNOL, MADRAS 600032, TAMIL NADU, INDIA

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 06期

关键词：

D O I：

10.1016/0957-4166(96)00183-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A novel method to produce (R)-(-)-2-hydroxy-4-phenylbutanoic acid ethyl ester 1b has been developed. 2-Oxo-4-phenylbutanoic acid ethyl ester 1a is reduced to 1b by the cell cultures of Daucus carota in high enantiomeric excess and yield. (C) 1996 Elsevier Science Ltd

引用

页码：1571 / 1572

页数：2

共 17 条

[11]

SCHMIDT E, 1992, NATO ADV SCI I C-MAT, V381, P377

[12] BIOTRANSFORMATION OF EXOGENOUS SUBSTRATES BY PLANT-CELL CULTURES [J].

SUGA, T ;

HIRATA, T .

PHYTOCHEMISTRY, 1990, 29 (08) :2393-2406

[13] ENANTIOSELECTIVITY IN THE HYDROLYSIS OF BICYCLIC MONOTERPENE ACETATES WITH THE CULTURED-CELLS OF NICOTIANA-TABACUM [J].

SUGA, T ;

HIRATA, T ;

IZUMI, S .

PHYTOCHEMISTRY, 1986, 25 (12) :2791-2792

[14] ENANTIOSELECTIVITY IN THE BIOTRANSFORMATION OF BICYCLO[3.1.1]HEPTANES WITH THE CULTURED-CELLS OF NICOTIANA-TABACUM [J].

SUGA, T ;

HAMADA, H ;

HIRATA, T .

CHEMISTRY LETTERS, 1987, (03) :471-474

[15] PREPARATION OF ENANTIOMERICALLY ENRICHED COMPOUNDS BY USING ENZYMES .9. A SIMPLE PREPARATION OF (R)-2-HYDROXY-4-PHENYL-BUTANOIC ACID [J].

SUGAI, T ;

OHTA, H .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1991, 55 (01) :293-294

[16] A FAVORABLE DIASTEREOSELECTIVE SYNTHESIS OF N-(1-S-ETHOXYCARBONYL-3-PHENYLPROPYL)-S-ALANINE [J].

URBACH, H ;

HENNING, R .

TETRAHEDRON LETTERS, 1984, 25 (11) :1143-1146

[17] LIPASE-CATALYZED IRREVERSIBLE TRANS-ESTERIFICATION USING ENOL ESTERS - RESOLUTION OF CYANOHYDRINS AND SYNTHESES OF ETHYL (R)-2-HYDROXY-4-PHENYLBUTYRATE AND (S)-PROPRANOLOL [J].

WANG, YF ;

CHEN, ST ;

LIU, KKC ;

WONG, CH .

TETRAHEDRON LETTERS, 1989, 30 (15) :1917-1920

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