Botulinum toxin A versus fixed cast stretching for dynamic calf tightness in cerebral palsy

被引:121
作者
Flett, PJ
Stern, LM
Waddy, H
Connell, TM
Seeger, JD
Gibson, SK
机构
[1] Womens & Childrens Hosp, N Adelaide, SA 5006, Australia
[2] Crippled Childrens Assoc S Australia Inc, Adelaide, SA, Australia
关键词
botulinum toxin A; calf tightness; cerebral palsy; fixed cast stretching;
D O I
10.1046/j.1440-1754.1999.00330.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective: To compare botulinum toxin A injections with fixed plaster cast stretching in the management of cerebral palsied children with dynamic (i.e. non-fixed) calf tightness. Methods: The settings were the Women's and Children's Hospital (WCH) and the Crippled Children's Association of South Australia (CCA), Adelaide, South Australia. Twenty children were selected by two paediatric rehabilitation specialists. A prospective, randomized, single-blind controlled study, was carried out, with 10 children in each arm. The clinicians were blinded as to the allocated interventions. The outcome measures for 6 months post intervention were clinical assessment, modified Ashworth Scale, Gross Motor Function Measure, 2 D-video ratings using a modified Physical Rating Scale and a global scoring scale and a parent satisfaction questionnaire. Results and Conclusion: Botulinum toxin A injections were of similar efficacy to serial fixed plaster casting in improving dynamic calf tightness in ambulant or partially ambulant children with cerebral palsy. The ease of outpatient administration, reduction of muscle tone and safety with botulinum toxin A was confirmed. Parents consistently favoured botulinum toxin A and highlighted the inconvenience of serial casting.
引用
收藏
页码:71 / 77
页数:7
相关论文
共 16 条
[1]   Botulinum toxin A compared with stretching casts in the treatment of spastic equinus: A randomised prospective trial [J].
Corry, IS ;
Cosgrove, AP ;
Duffy, CM ;
McNeill, S ;
Taylor, TC ;
Graham, HK .
JOURNAL OF PEDIATRIC ORTHOPAEDICS, 1998, 18 (03) :304-311
[2]  
CORRY IS, 1995, DEV MED CHILD NEUROL, V37, P20
[3]  
COSGROVE AP, 1994, DEV MED CHILD NEUROL, V36, P386
[4]  
GAUCHER EJ, 1993, TOTAL QUALITY HLTH C
[5]  
Hanson R, 1994, J Qual Clin Pract, V14, P137
[6]   BRIEF CHILD PSYCHIATRIC EVALUATION - PARENTAL SATISFACTION AND COMPLIANCE [J].
JELLINEK, MS .
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1986, 25 (02) :266-268
[7]   MANAGEMENT OF SPASTICITY IN CEREBRAL-PALSY WITH BOTULINUM-A TOXIN - REPORT OF A PRELIMINARY, RANDOMIZED, DOUBLE-BLIND TRIAL [J].
KOMAN, LA ;
MOONEY, JF ;
SMITH, BP ;
GOODMAN, A ;
MULVANEY, T .
JOURNAL OF PEDIATRIC ORTHOPAEDICS, 1994, 14 (03) :299-303
[8]  
KOMAN LA, 1996, J CHILD NEUROL S1, V11, P423
[9]  
LOCKER D, 1978, SOC SCI MED-MED SOC, V12, P283, DOI 10.1016/0160-7979(78)90210-2
[10]  
PEKARIK G, 1992, J CLIN PSYCHOL, V48, P91, DOI 10.1002/1097-4679(199201)48:1<91::AID-JCLP2270480113>3.0.CO