SplicePort - An interactive splice-site analysis tool

被引：169

作者：

Dogan, Rezarta Islamaj ^{[1
,2
]}

Getoor, Lise ^{[1
]}

Wilbur, W. John ^{[2
]}

Mount, Stephen M. ^{[3
,4
]}

机构：

[1] Univ Maryland, Dept Comp Sci, College Pk, MD 20742 USA

[2] NIH, Natl Lib Med, Natl Ctr Biotechnol Informat, Bethesda, MD 20894 USA

[3] Univ Maryland, Ctr Bioinformat & Computat Biol, College Pk, MD 20742 USA

[4] Univ Maryland, Dept Mol Genet & Cell Biol, College Pk, MD 20742 USA

来源：

NUCLEIC ACIDS RESEARCH | 2007年 / 35卷

基金：

美国国家科学基金会;

关键词：

D O I：

10.1093/nar/gkm407

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

SplicePort is a web-based tool for spliceanalysis that allows the user to make splicepredictions for submitted sequences. In the user can also browse the rich catalog of that underlies these predictions, and which we found capable of providing high accuracy on human splice sites. Feature is optimized for human splice sites, but the features are likely to be predictive for mammals as well. With our interactive browsing and visualization tool, the user can and explore subsets of features used in spliceprediction (either the features that account for classification of a specific input sequence or complete collection of features). Selected sets can be searched, ranked or displayed The user can group features into clusters frequency plot WebLogos can be generated each cluster. The user can browse the clusters and their contributing elements, for new interesting signals, or can validate observed signals. The SplicePort server can be accessed athttp://www.cs.umd.projects/SplicePort and http://www.spliceport.org.

引用

页码：W285 / W291

页数：7

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