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Human pluripotent stem cells: a progress report

被引：25
作者：
Pera, MF [1 ]
机构：
[1] Monash Univ, Monash Inst Reprod & Dev, Melbourne, Vic 3168, Australia
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 05期
关键词：
D O I：
10.1016/S0959-437X(00)00238-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The derivation of diploid human pluripotent stem cell lines from either human blastocysts or embryonic gonads in 1998 attracted a great deal of interest because of the widespread potential applications of these cells in research and in regenerative medicine. Since the initial reports, there has been some progress in the characterisation of blastocyst-derived stem cells, and some technical advances in their manipulation. Conditions for differentiation in vitro of pluripotent stem cells from either blastocysts or gonads have been defined. In some studies, committed progenitor cell populations have been isolated from mixed cultures of differentiating ES cells.
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页码：595 / 599
页数：5
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